Example sentences for: adenomas

How can you use “adenomas” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The NSAID sulindac has been shown to cause regression of colorectal adenomas of patients with hereditary forms of polyposis (Familial Adenomatous Polyposis (FAP) and Gardner's Syndrome) [ 17 18 19 ] and in sporadic colorectal adenomas [ 20 ] . In addition, case reports have demonstrated that indomethacin and sulindac were effective co-therapy agents in the treatment of desmoid tumours [ 21 22 ] . Finally, the inclusion either of indomethacin, naproxen or sulindac in the chemotherapy regiment of gastric carcinoma patients resulted in a significant increase in survival; 30 months versus 6 months when NSAIDs included in treatment regime [ 22 ] .

  • p27 Kip1knockout mice display internal organ hyperplasia and are highly prone to pituitary adenomas [ 5 6 7 ] . In human cancers, such as breast [ 8 ] , prostate [ 9 ] , colorectal [ 10 ] , and others, low levels of p27 Kip1expression correlate with decreased survival rates.

  • Aspirin administration also resulted in a significant increase in the number of apoptotic cells found in small intestinal adenomas (figure 3).

  • Various studies have reported increased levels of prostaglandins and COX-2 expression in colorectal adenomas and adenocarcinomas obtained both from animals [ 40 41 ] and humans [ 42 43 44 ] . These findings have lead to the implication that COX-2 plays an important role in intestinal neoplasia and that the anti-neoplastic effects of NSAIDs are attributable to their ability to inhibit COX-2.

  • Large intestinal adenomas as large as 5-6 mm in diameter were occasionally seen.


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