Words similar to adenine
Example sentences for: adenine
How can you use “adenine” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the case of disruption of the Fhit and Hnt2-homologous aph1 gene in S. pombe , which encodes an enzyme relatively specific for a AppppA [ 20 ] , a 290-fold increase in AppppA concentration was observed [ 22 ] . Our data indicate that Hnt2 hydrolyzes ApppN and AppppN in vivo in budding yeast and that an intact adenine biosynthetic pathway is required for high-level synthesis and accumulation of adenylylated dinucleoside polyphosphates.
The presence of cardiolipin has been implicated in the function of numerous mitochondrial proteins including, sites I and III of the electron transport chain, the adenine nucleotide transporter, the protein translocation machinery, and the localization of mitochondrial creatine kinase [ 19 20 21 22 ] .
Recently, discovery that the Hint-homologous HNT1 gene is required for high temperature growth on galactose and observations that alleles of cak1 , kin28 , ccl1 and tfb3 are hypersensitive to loss of Hnt1 enzyme activity provided evidence that Hnt1 enzyme activity positively regulates Kin28 function, particularly on galactose media [ 9 ] . Though phenotypic consequences of hnt2 mutations have yet to be discovered, our observations suggest that synthetic lethal interactions with hnt2 mutations are likely to be found in adenine prototrophic strains undergoing heat shock.
Nicotinamide-adenine dinucleotide (NAD), riboflavin (vitamin B 2 ), flavin mononucleotide (FMN), flavin adenine dinucleotide (FAD), and DCIP were purchased from Sigma (St.
Here we discover a requirement of adenine biosynthesis for high-level dinucleoside polyphosphate accumulation in the absence of the Fhit homolog in S. cerevisiae . By constructing active site mutants of Hnt2 that were expressed in yeast, we demonstrate that ApppN and, to a lesser degree, AppppN levels are controlled by the Hnt2 active site.
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