Example sentences for: adenine

How can you use “adenine” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Signal probes (Table 2) tagged with eight ferrocenes were synthesized with a modified adenine residue (N6) containing a ferrocene substitution on the ribose ring [ 11 ] . No signal probes were synthesized for HPV types 33, 39, 55, and 73.

  • 037 mg/ml, Fisher Scientific, Fair Lawn, NJ, USA) and the reduced form of β-nicotinamide adenine dinucleotide (0.

  • Some cases of HSP result from mutations in the gene for paraplegin, a nuclear-encoded mitochondrial metalloprotease, including: a 2 bp deletion at position 784, which causes a frameshift that eliminates 60% of the protein; and an adenine insertion at position 2,228 of the paraplegin cDNA, which creates a frameshift resulting in truncation of the last 57 residues of this 795-residue protein [ 37].

  • CC-1065 (Figure 1) is among the most potent antitumor agents discovered [ 9 10 11 12 13 ] . It binds to double-stranded B-DNA within the minor groove with a sequence preference for 5'-d(A/GNTTA)-3' and 5'-d(AAAAA)-3', and alkylates the N3 position of the 3'-adenine with its left-hand CPI segment [ 14 15 ] . CC-1065 also inhibits gene transcription by interfering with binding of the TATA box-binding protein to its target DNA [ 16 ] . Despite its high potency and broad spectrum of antitumor activity, CC-1065 cannot be used in humans because it causes delayed death in experimental animals [ 17 ] . To pursue compounds possessing the potent antitumor activity but devoid of the toxic side effects of the parent compound, many CC-1065 analogues have been synthesized [ 18 19 20 21 22 23 24 25 26 ] .

  • The tumor promoter phorbol myristate acetate (PMA) has been shown to activate the NADPH (nicotinamide adenine dinucleotide phosphate) oxidase and initiate the oxidative burst response in various phagocytes, including neutrophils and the macrophage-like cell line J774A.


How many words do you know? Try our free vocabulary size test!


Search

Search for example sentences

Loading Loading...
Quantcast