Example sentences for: upregulation

How can you use “upregulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • One study performed a DNA microarray analysis on CMV infected cells and observed an upregulation of 258 cellular mRNAs whose level changes were by a factor of 4 or more after the onset of viral replication [ 76 ] . The functions of some of these genes still remains highly speculative, yet it gives an insight as to what potential roles these genes may play, particularly in EBV reactivation.

  • Ectopic BMP4 can lead to the upregulation of Tbx5 in the retina, and Tbx5 misexpression results in altered retinal ganglion cell axon projections to the tectum [ 56 ] .

  • To determine whether upregulation of cytokine production by CSC involved activation of NFκB, we examined CSC-treated epithelial cells for phosphorylation of the inhibitor of NFκB (IκB).

  • These findings indicate that in humans with DNP, diabetes-induced upregulation of CD36 expression in proximal tubules was associated with moderate to advanced stages of TED and IF.

  • The eleven genes with the lowest (array) P -values are presented in Table 2. The upregulation by mefloquine of transcripts encoding the transcription factors cJun and IkappaB (IkB) and the ER stress protein GADD153 were confirmed by RT-PCR (Table 2, Figure 2).


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