Example sentences for: upregulation

How can you use “upregulation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Second, different cell adhesion and ECM-related genes are upregulated in tumors of different cell types (A549 versus U118); if the upregulation were due to a common mouse source, then the same genes should have appeared upregulated in both cell types, given that the cells were grown in the same site.

  • To determine whether upregulation of cytokine production by CSC involved activation of NFκB, we examined CSC-treated epithelial cells for phosphorylation of the inhibitor of NFκB (IκB).

  • This upregulation of tyrosine phosphorylation was inhibited by preincubation with a TGFβ 1 neutralizing antibody or by blocking of α V β 6 integrin, thus again proving mature TGFβ 1 as an initial signaling ligand for α V β 6 .

  • Hyal-2-increased TNF susceptibility in L929 cells appears to be associated with 1) Hyal-2 upregulation of the proapoptotic WOX1, 2) Hyal-2 migration to the mitochondria during apoptotic cell death, and 3) the prolonged IκBα degradation and NF-κB activation in Hyal-2-expressing cells stimulated with TNF.

  • Because anesthetization depresses ventilatory drive, and because hypoxia can also induce VEGF mRNA upregulation, great care was taken in the electrical stimulation protocol to ensure that animals were adequately mechanically ventilated.


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