Words similar to upregulating
Example sentences for: upregulating
How can you use “upregulating” in a sentence? Here are some example sentences to help you improve your vocabulary:
IL-4 can downregulate the production of proinflammatory and T-helper (Th)1-type cytokines by inducing mRNA degradation and upregulating the expression of inhibitors of proinflammatory cytokines such as IL-1 receptor antagonist (IL-1Ra) [ 3, 4].
In essence, these results demonstrate that NHBEs respond to moderate doses of CSC by activating both the ERK1/2 and the NFκB pathways, and by upregulating the expression of several genes encoding proinflammatory molecules.
IL-4 can down-regulate the production of proinflammatory and Th1-type cytokines by inducing mRNA degradation and upregulating the expression of inhibitors of proinflammatory cytokines such as IL-1Ra [ 3, 4].
Not only can these factors damage DNA and host tissues but can modulate inflammatory reactions [ 60 ] and stimulate apoptosis [ 64 ] , a major mechanism leading to loss of CD4 +T cells [ 65 ] . TNF-α also has the capacity to perturb the clinical condition in AIDS by strongly upregulating the transcription of the HIV genome [ 66 ] . In fact, it has been proposed [ 67 ] that AIDS is in many ways a TNF-α disease since this cytokine it is a potent activator of NF-kB, and an inducer of HIV genome transcription and apoptosis in HIV-infected T cells.
5 ng/ml and 5 ng/ml) were also found (data not shown) to be equally effective in upregulating α-SMA in accordance with other data [ 45 46 ] .