Words similar to upregulating
Example sentences for: upregulating
How can you use “upregulating” in a sentence? Here are some example sentences to help you improve your vocabulary:
IL-4 can down-regulate the production of proinflammatory and Th1-type cytokines by inducing mRNA degradation and upregulating the expression of inhibitors of proinflammatory cytokines such as IL-1Ra [ 3, 4].
In essence, these results demonstrate that NHBEs respond to moderate doses of CSC by activating both the ERK1/2 and the NFκB pathways, and by upregulating the expression of several genes encoding proinflammatory molecules.
Previous work has suggested that although SERCA expression in limb muscles seems to respond to increases in functional load by upregulating SERCA 2 (the slow SERCA isoform) and downregulating SERCA 1 (the fast isoform) [ 50 ] , similar responses might not occur in diaphragm [ 51 ] . Our data showing no difference in the expression of SERCA 1 and SERCA 2 between emphysematous and control animals are consistent with this finding.
Not only can these factors damage DNA and host tissues but can modulate inflammatory reactions [ 60 ] and stimulate apoptosis [ 64 ] , a major mechanism leading to loss of CD4 +T cells [ 65 ] . TNF-α also has the capacity to perturb the clinical condition in AIDS by strongly upregulating the transcription of the HIV genome [ 66 ] . In fact, it has been proposed [ 67 ] that AIDS is in many ways a TNF-α disease since this cytokine it is a potent activator of NF-kB, and an inducer of HIV genome transcription and apoptosis in HIV-infected T cells.
5 ng/ml and 5 ng/ml) were also found (data not shown) to be equally effective in upregulating α-SMA in accordance with other data [ 45 46 ] .
Loading...