Example sentences for: upregulates

How can you use “upregulates” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Mefloquine upregulates the transcription of important ER stress response genes

  • For instance, exposure of fibroblast-like marrow MSCs in vitro to optimal concentrations of dexamethasone, ascorbic acid and β-glycerophosphate induces a cuboidal morphology, upregulates AP and osteocalcin expression, and a mineralized (hydroxyapatite) matrix [ 20].

  • Our results show that stimulation of primary cultures of human lung fibroblasts with the proximal cytokine IL-1β upregulates COX-2 protein and mRNA expression to a similar degree in normal and IPF fibroblasts.

  • The first of these examples is the OxyR transcription factor, which upregulates peroxide defenses in

  • Additionally, C-reactive protein reduces endothelial nitric oxide synthase, upregulates the proatherosclerotic NF-κB pathway, enhances low-density lipoprotein (LDL) uptake by macrophages, which become foam cells, and facilitates T-cell- and complement-mediated destruction and apoptosis of the endothelium [2,26,29–31].


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