Example sentences for: upregulated

How can you use “upregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Most are constitutively expressed at low levels in almost all cell-types, but a number are upregulated in response to cellular stresses and these are known as the heat shock proteins (HSPs).

  • Previous studies have demonstrated that acute endotoxemia activates peripheral blood neutrophils to release prostaglandins [ 17 ] . These lipid mediators are produced during inflammatory reactions largely via the enzyme COX-2 [ 18 ] . We found that COX-2 mRNA was markedly upregulated (40-400 fold) in adherent vascular lung neutrophils following endotoxin treatment of the animals (Fig.

  • Among these 19 genes, those for NKG5, T-cell receptor α chain, and HLA class II related transcripts appeared of particular interest because they have been found to be upregulated in the context of acute rejection of renal allografts [ 23, 24].

  • It was originally characterized as a powerful macrophage activator that upregulated nitric oxide (NO) production and MHC expression in macrophages [ 16 ] . It has since been shown to stimulate antiviral and antibacterial activities, to differentiate Th0 cells toward Th1 fates, and to activate endothelial cells for leukocyte adhesion (reviewed in [ 17 18 ] ).

  • Although these data sets are not completely complementary, we identified one gene that is significantly upregulated in the colon relative to ovary ( PLAB , coding for prostate differentiation factor; Hs.


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