Example sentences for: upregulated

How can you use “upregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 2003), while notch-1b and its ligand, deltaC , are upregulated during zebrafish heart and fin regeneration (Raya et al.

  • The internal elastic lamella of arteries is shown to form gaps prior to vessel dilatation in an experimental arteriovenous model in rabbit carotid artery [ 2 ] . Collagenase and matrix metalloproteinases (MMPs) have been observed to be upregulated during vessel dilation either in flow-induced model [ 10 ] or in a post-stenotic dilatation [ 11 ] .

  • Twenty known genes were chosen from among the five clusters for this analysis; the majority were selected from cluster A, which contained the largest number of the most highly upregulated genes.

  • AKT1 is over-expressed in gastric adenocarcinomas and breast cancer cell lines, AKT2 is amplified and over-expressed in pancreatic, ovarian, and breast cancers, and AKT3 is upregulated in estrogen receptor-deficient breast cancer and in androgen-independent prostate cell lines [reviewed in ref.

  • This is similar to the enhanced translation of certain yeast and mammalian mRNAs (GCN4, ATF4, both transcription factors regulated by GCN2) when GCN2 in these organisms is activated by amino acid starvation, even though bulk mRNA undergoes a decrease in translation efficiency [ 24 25 ] . The hallmark of mRNAs that are upregulated by GCN2 and eIF2α phosphorylation is the presence of several upstream open reading frames within their 5' UTRs.


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