Words similar to upregulated
Example sentences for: upregulated
How can you use “upregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:
Lastly, the cyclin-dependent kinase inhibitor p27 was upregulated by IL-4 in the monkey lung.
c- myc was upregulated in K562 cells overexpressing BP1, and c-Myc protein is highly expressed in more than half of breast cancer patients [ 36 ] . Cyclin D2, downregulated on the array, is repressed in breast cancer [ 37 ] . It will be important to determine whether either of those genes is a target for BP1 in breast cancer.
It has been reported that CCR5 expression is upregulated in RA synovial fluid and synovial tissue T cells [ 10, 11, 12] and that CCR5 Δ 32 deletion may have an influence on clinical manifestations of RA [ 13], suggesting that CCR5 might play an important role in RA.
For example, the murine Hoxa-1 gene is upregulated in neoplastic murine mammary glands [ 18 ] . In humans, the lack of HOXA5 expression results in the loss of p53 expression in breast cancer [ 19 ] . Enforced HOXB7 expression in SkBr3 breast cancer cells induces the expression of basic fibroblast growth factor and increases growth rate, serum-independent growth, and the ability of cells to form colonies in semisolid medium [ 20 ] . Nude mice, when injected with SkBr3/HOXB7 cells, developed tumors [ 21 ] .
As illustrated by Figures 3and 4, in the cell-cycle phase M/G1, CDC46 (encoding part of the replication complex) was selected as an upregulated gene, whereas the histone genes HTB2, HTA2 and HHO1 (also marked by Spellman et al . [ 23] and Fellenberg et al . [ 14]) were selected as downregulated genes.