Example sentences for: upregulated

How can you use “upregulated” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We therefore hypothesized that NOS isoforms are upregulated following hypoxia and that this may account for the increased susceptibility to hypoxic pulmonary hypertension in mice that lack eNOS [ 9, 12].

  • At 4 h after challenge, the highest number of downregulated cDNA elements (92) was observed, while the highest number of upregulated cDNA elements (51) was seen in the IL-4-challenged monkey.

  • Msx genes are upregulated in regenerating salamander limbs and regenerating zebrafish fins and hearts (Simon et al.

  • As illustrated by Figures 3and 4, in the cell-cycle phase M/G1, CDC46 (encoding part of the replication complex) was selected as an upregulated gene, whereas the histone genes HTB2, HTA2 and HHO1 (also marked by Spellman et al . [ 23] and Fellenberg et al . [ 14]) were selected as downregulated genes.

  • Also of interest are genes that are upregulated in both the cancers, including IGFBP3 (insulin-like growth factor binding protein 3), which, interestingly, is thought to have proapoptotic activities [ 14 ] , and GSN (gelsolin), which has a role in cellular motility and acts as both a regulator and effector of apoptosis [ 15 ] . Further xenograft studies of the type presented here could examine the responses of the host tissue to the tumor (using a mouse microarray chip), as well as temporal changes in gene expression within the developing tumor.


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