Words similar to upregulate
Example sentences for: upregulate
How can you use “upregulate” in a sentence? Here are some example sentences to help you improve your vocabulary:
For instance, IL-1-degraded cartilage tissues and cell suspensions are frequently employed as model systems to study cartilage metabolism under osteoarthritis-like conditions [ 1 2 3 4 ] and to assess the efficacy of various drug therapies [ 5 6 7 8 9 ] . IL-1 signals cells via cell surface receptors to upregulate proteases, matrix metalloproteinases and aggrecanase, while downregulating matrix metalloproteinase inhibition and proteoglycan synthesis [ 10 11 ] . The ultimate effect of these metabolic changes include damage to the ECM, loss of ECM components (especially proteoglycan), and alteration of the normal balance of catabolic and anabolic processes that regulate cartilage ECM composition.
In order to ascertain regional and fiber type patterns of VEGF mRNA production in those muscles stimulated to upregulate VEGF, 4 each of treadmill exercised and electrically stimulated muscle samples, and 2 control muscles, were successfully processed through in situ hybridization.
The host should upregulate genes that defend it against infection and the pathogen should upregulate genes that it needs to attack.
Similarly, retinoids can upregulate TGF-β production and activation, both in cell culture and in rats in vivo [ 16, 17].
Another potential explanation is tissue hypoxia, which has been suggested to upregulate Fas in the kidney [ 36 37 ] . MDCK cells in culture demonstrated increased expression of Fas, FasL and FADD in response to partial ATP depletion [ 40 ] . Fas and FasL expression in the kidney may serve as indicators of cellular stress.
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