Words similar to transcription
- transcribed
- transcript
- transcript-
- transcriptase
- transcriptase-
- transcriptase-polymerase
- transcriptase-polymerasechain
- transcriptases
- transcription
- transcription-
- transcription-independent
- transcription-polymerase
- transcription-profiling
- transcription-regulatory
- transcriptional
- transcriptionally
- transcriptomic
Example sentences for: transcription
How can you use “transcription” in a sentence? Here are some example sentences to help you improve your vocabulary:
Studies employing this approach have contributed to our understanding of diverse biological processes from yeast physiology [ 1 2 ] to human cancer [ 3 ] . More recently, microarray-based approaches have been used to characterize physical properties of the genome, for example, by mapping transcription factor binding sites [ 4 5 ] and histone modifications [ 6 7 ] .
P-TEFb phosphorylates the carboxy-terminal domain of the RNA polymerase II complex [ 12], facilitating transcription elongation.
These modifications include the direct binding of mRNA to magnetic oligo(dT) beads before the reverse transcription step, and a great reduction in the quantity of linkers used to generate ditags.
It is known that during clonal selection in the thymus, immature CD4, CD8 double positive cells develop into single positive CD4 or CD8 cells according to the relative affinity of their TCR to class II or class I molecules respectively [ 5 6 ] . These immature T-cells are selected in the thymic epithelium on the basis of their TCR interaction with either class I or class II MHC molecules [ 7 8 ] , thus generating two mutually exclusive subpopulations that are characterized by the expression of either CD4 or CD8 glycoproteins [ 9 ] . Earlier studies in the murine system have demonstrated that PMA and cAMP can modulate the expression CD4 and CD8 on developing thymocytes [ 10 11 12 13 ] . In keeping with these findings, ex vivo experiments with human thymocytes previously reported by our group, revealed that while phorbol esters can coordinately regulate the transcription of α and β TCR during intrathymic T cell differentiation [ 14 ] , cAMP selectively affected the transcription of the α and δ-TCR [ 15 16 ] . Together the murine data and our own findings support the hypothesis that in humans, TCR expression and CD4, CD8 commitment and selection may be regulated by the same signal-transduction pathways.
Thus, the precise onset of transcription of the transgene is uncertain.
Loading...