Example sentences for: transcriptionally

How can you use “transcriptionally” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • This observation led us to investigate the possibility that the class of genes that are transcriptionally induced by cellular signaling events is enriched for genes with labile mRNAs.

  • Various genes involved in cholesterol metabolism (microsomal transfer protein, MTP; apolipoprotein C3, Apoc3; cholesterol 7α hydroxylase, Cyp7a1), carbohydrate metabolism (pyruvate kinase; facilitative glucose transporter gene, GLUT2), and coagulation (vitamin K dependent coagulation factors VII, IX, X) have been previously found to be induced by PPARs [ 32 ] , but were not transcriptionally regulated in the present experiment.

  • An NCBI BLAST search identified the murine homologue of yeast ELO2 (Elovl2) to be Ssc2 (Sequence similarity to Cig30), predominating in liver and testes [ 62 ] ; complementation studies in yeast mutants indicated the functional equivalent of ELO3 (Elovl3) is Ssc1 [ 35 ] . Substrates of mouse Ssc2 were AA and EPA (DHA was not tested) [ 35 ] . Thus, FUNG and FISH feeding may transcriptionally regulate their subsequent conversion to elongated products.

  • However, these data must be interpreted in light of another novel observation, namely that even relatively simple, transcriptionally active, transgene loci can interact with nonlinear gene dosage effects that have characteristics of epigenetic trans-silencing.

  • For instance, at the b1 locus, one specific allele can switch spontaneously from a non-paramutagenic, transcriptionally active, state to a paramutagenic, transcriptionally silenced, state [ 23 ] . Whether the same is true for trans-silencing is not well established.


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