Example sentences for: transcriptional

How can you use “transcriptional” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • For the substantial subset of UniGene clusters for which the dominant transcriptional orientation was unannotated, we required that the misoriented ESTs be significantly overrepresented regardless of the correct orientation of the cluster.

  • Northern blotting validation of transcriptional regulation

  • Decreased growth factor and growth factor receptor expression has been proposed as a potential growth inhibitory mechanism [ 14 ] . Additionally, RA mediated inhibition of AP-1 activity is believed to be important in cellular growth control by this ligand [ 13 ] . AP-1 inhibition via direct interaction between RARs and AP-1 proteins has been proposed [ 16 ] . RA inhibition of jun N-terminal kinase was shown to prevent c-jun phosphorylation, resulting in decreased AP-1 activity [ 17 ] . Competition between RAR and AP-1 for limiting amounts of the nuclear receptor coactivator CBP may also account for decreases in AP-1 transcriptional activity [ 5 ] . In the present study we have described a new mechanism by which RA can inhibit cellular proliferation.

  • This demonstrates that NFATp is a bona fide transcriptional activator.

  • Paramutation has been studied extensively for four maize loci that encode transcriptional regulators of pigment biosynthesis [ 1 ] . Paramutation has also been investigated in the Arabidopsis PAI gene family, at the a1 and chalcone synthase (CHS) transgene loci in petunia, and in a number of other cases [ 2 3 4 ] . The Arabidopsis resistance gene BAL/CPR1 displays a related form of epigenetic instability [ 5 6 ] . Interactions resembling paramutation also occur among non-allelic transgene loci with DNA sequence homology.


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