Example sentences for: transcriptional

How can you use “transcriptional” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • We obtained samples from adjacent tumors from a single individual, and compared the transcriptional profile of each tumor.

  • These stages vary greatly in morphology, biochemical properties, and transcriptional activity (reviewed in [ 15, 37]).

  • A highly ordered chromatin structure presents a physical obstacle for gene transcription; presumably by limiting the access of transcription factors and RNA polymerase II core machinery to target DNA [ 82 83 ] . In concert with the observation that corepressors are associated with HDAC activities [ 84 85 ] , it appears that the transcriptional outcome of nuclear receptors is determined by the balance of histone acetylation and deacetylation activities, and that ligands serve as a switch to recruit HATs with the concomitant dismissal of HDACs.

  • GSK3β can increase p53's transcriptional activity in vivo, and this activation requires serines 33 and 37 of the p53 protein.

  • The large number of genes meagerly expressed compared to wild type in both deletion mutants is consistent with the roles of Snf2p and Swi1p as transcriptional activators.


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