Words similar to tem
Example sentences for: tem
How can you use “tem” in a sentence? Here are some example sentences to help you improve your vocabulary:
There were also no structures resembling the intra-nuclear annulate lamellae observed in some nup mutants [ 24 36 ] . Samples analyzed by TEM over a time course after shift to 34° showed that the membrane proliferation paralleled the GFP-Nup mislocalization seen by fluorescence microscopy (data not shown).
Employing transmission electron microscopy (TEM) in an additional study [ 9 ] , extensive fiber cell damage was noted in the outer adult nucleus of late-onset diabetic cataractous lenses, with minimal morphological disturbances in the inner nuclei.
Earlier studies identified tab2 and TAB6 as mutations in NET1 and CDC14, respectively [ 15 18 ] . Net1 detains Cdc14 in the nucleolus and inactivates it until a Tem1-dependent signal sets Cdc14 free to promote exit from mitosis [ 15 16 17 ] . The fact that both Net1 and Cdc14 are directly involved in exit from mitosis prompted us to further analyze tab mutants.
Having established that tab3-1 indeed bypassed Tem1 deficiency at a cellular level, we tested whether Sic1 accumulation and Clb2 degradation, two hallmark events that accompany exit from mitosis, also occurred.
Cdc5 is required for full activation of the Dbf2-Mob1 protein kinase complex [ 15 16 17 ] , and has been proposed to impinge on the MEN both upstream and downstream of Tem1 [ 15 16 17 18 ] . During exit from mitosis, Cdc5 is required for Clb2 destruction, and similar to over-expression of Cdc14 [ 3 ] , induction of Cdc5 triggers precocious Clb2 degradation in pre-anaphase cells [ 19 20 ] . In addition to its role in exit from mitosis, Cdc5 has other functions during mitosis in budding yeast.
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