Example sentences for: telomeric

How can you use “telomeric” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • gov/genome/guide/human), D1S425 lies 4 Mb telomeric of D1S245.

  • In addition, other studies have revealed a functional role for checkpoint Rad proteins in telomere maintenance [ 43 44 ] , while one has shown that an over-expressed, epitope tagged version of Rad3 associates with telomeric DNA [ 44 ] . It will be interesting to determine if checkpoint proteins have a role in centromere function, or mating-type silencing, both of which require intact heterochromatic structures.

  • Immediately telomeric to APBA2 lies another gene (KIAA0574; see Figure 2a), which was initially identified from a sequencing project of large, brain-derived cDNAs [ 25 ] . KIAA0574 encodes a protein of unknown function, and is transcribed in the opposite orientation relative to APBA2 . BLASTP using the KIAA0574 predicted amino acid sequence detects weak homology (35% identity, 64% similarity over 69 residues) to a protein termed X123, the gene for which is located in the 9q12.

  • The next challenge - sequence completion and verification - requires the closing of the gaps between contigs, isolation and characterization of centromeric and telomeric regions that are poorly represented in libraries, and verification of contig assembly.

  • MMP15 and SCYA17 were located telomeric to D16S408 and thus outside the Blau syndrome interval and were excluded from further studies.


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