Example sentences for: telomere

How can you use “telomere” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Assuming that some promoter element is required and is not provided by the 3-5 bp 5' of the transcription start, perhaps the telomere repeats serve this purpose (see [ 64 ] ). It is also possible that a promoter element resides internal to this region: we have identified a highly conserved sequence block in the gene's first intron and suggested that it might serve as a promoter element [ 65 ] .

  • Sequences that function as ARS s in yeast occur on average every 20 to 40 kb in all the eukaryotic genomes thus far examined [ 14 15 ] , which suggests that most mammalian chromosomal regions can be readily isolated by TAR-cloning with a vector that lacks an ARS . The ARS frequency in chromosomal regions that consist of multiple repetitive elements, however, such as the centromere and telomere, may be reduced, meaning that these regions may not be isolatable by the original TAR method.

  • double-strand cutting activity, and thereby explaining coupled action between chromatid cutting and telomere addition (see below).

  • LM-PCR, ligation-mediated polymerase chain reaction; MAC, macronucleus; MIC, micronucleus; TASs, telomere addition sites; CR-R, CR-L, Common Region-Right, -Left.

  • An analogous sequence, E-cbs, has been characterized in Euplotes by sequence comparisons and analyses of DNA intermediates and products of MAC development [ 37 38 39 ] . At a fixed distance from itself, E-cbs directs a 6-nucleotide staggered cut, with a protruding 3'OH to which telomerase adds telomere repeats.


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