Example sentences for: substrate

How can you use “substrate” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • However, in L1, Asn233 is 14 Å away from the modeled position of the substrate β-lactam carbonyl [ 37 ] . To test the role of Asn233 in substrate binding, the Asn was changed to a leucine (N233L) and to an aspartic acid (N233D), and these mutants were characterized by using metal analyses, CD spectroscopy, steady-state kinetics, and pre-steady state kinetic studies.

  • cPLA 2 -mediated AA release must be preceded by translocation of the enzyme to its membrane substrate which is a Ca 2+-dependent process and is a function of the calcium-dependent lipid-binding (C2) domain.

  • The I164A mutant exhibited increased K m values only when using cefoxitin as the substrate, suggesting an interaction of the isoleucine group with the methoxy group on cefoxitin.

  • The first involved PCR amplification from either PAC 61J10 (for TMOD2 ) or BAC HB342I3 (for TMOD4 and YL-1 ) using primers within each exon to amplify the exon and the intervening intron and use it as a substrate for sequencing the exon-intron boundaries.

  • As the tyrosine phosphorylated Cas substrate domain acts as a dominant negative for v-crk mediated transformation and JNK activation, and can also interact with v-crk and c-crk (data not shown), we wanted to determine if it could compete for binding of v- and c-crk to endogenous Cas.


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