Words similar to substrate
Example sentences for: substrate
How can you use “substrate” in a sentence? Here are some example sentences to help you improve your vocabulary:
In vivo , the introduction of ALDH1A1 mRNA into Xenopus embryos induces early synthesis of retinoic acid, while ALDH1A1 expression is detected during the tail bud stages of Xenopus embryogenesis [ 14 ] . ALDH1A2 in the mouse [ 15 ] and rat [ 16 ] has shown even greater specificity and catalytic efficiency for retinal as a substrate.
Tyrosine phosphorylation of the substrate domain leads to the recruitment of other downstream adaptors such as crk and nck, as well as other downstream effectors possessing SH2 domains, and signaling events attributed to this domain include activation of the JNK MAPK pathway and control of adhesion and migration of cells [ 6 10 16 38 44 ] . We constructed a chimera between a kinase that phosphorylates Cas in vivo and the substrate domain of Cas, in order to determine events regulated by this domain.
ANOVA = analysis of variance; Erk= extracellular signal-regulated kinase; IC 50 = half-maximal inhibition; IRS = insulin receptor substrate; LDH = lactate dehydrogenase; MAPK = mitogen-activated protein kinase; MEK = MAPK/extracellular signal-regulated kinase kinase; mTOR = mammalian target of rapamycin; PBS = phosphate-buffered saline; PI 3-kinase = phosphatidylinositol 3-kinase; RDS = respiratory distress syndrome; SD = standard deviation of the mean; SE = standard error of the mean; SP = surfactant protein; TPA = 12-
, resistance exercise training), substrate availability (e.g.
The inability to propose a consistent binding model also supports the recent proposal that different substrates of L1 are hydrolyzed by different mechanisms and further suggests that using steady-state kinetic constants may not be a valid way to probe substrate binding to L1.
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