Example sentences for: substitution

How can you use “substitution” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • These sequences indicate that function has sometimes been eliminated, initially through a small deletion or substitution, with the remaining DNA sequence subsequently eroded by multiple mutations that are biased in favor of deletion over insertion, as documented for Rickettsia [ 7, 9] and other bacteria including Buchnera [ 21].

  • One of the factors cited for the decline in personal mail volume is falling long distance telephone rates which have made telephone communication more affordable and fostered substitution of telephone calls for personal mail.

  • Mutating the conserved leucine to arginine at position 156 is a drastic change, disrupting a γ-branched aliphatic residue with a basic guanidino group, a major chemical and presumably structural substitution.

  • This experiment provides a positive in vivo selection for validation of the hypothesis, in contrast to the dramatic decrease in accumulation of the proteins when ligands are removed by substitution with non-ligand amino acids [ 42 ] . Furthermore, whereas stable complexes can be achieved by reconstitution with wild-type Lhcb1 and only Chl b but not only Chl a [ 37 43 ] , the hypothesis predicts that stable complexes can be reconstituted with the mutant protein containing these substitutions and Chl a.

  • The substitution rates for orthologous gene pairs were calculated using the same approach.


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