Example sentences for: substitution

How can you use “substitution” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In at least most cases, weak and null alleles appear to be due to substitution polymorphisms within the primer annealing sites [ 6 ] . They can be repaired by sliding the offending PCR primer to a nearby position along the chromosome.

  • Or retailers might not even notice if an unplanned substitution had been made because their information systems were equally as primitive.

  • Finally, transcription factors can alter local chromatin structure by modifying histones (typically through methylation, acetylation, and substitution of histone subunits) to permit or restrict access to the DNA.

  • The Gly145 → Arg substitution does not disrupt an absolutely conserved position as serine is also permitted, but it introduces a large, basic (and partly hydrophobic) residue that presumably diminishes at least one key function of TP.

  • For W89, an alanine substitution has been shown to prevent binding of [ 3H]granisetron; therefore a less severe mutation was constructed.


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