Words similar to substitutions
Example sentences for: substitutions
How can you use “substitutions” in a sentence? Here are some example sentences to help you improve your vocabulary:
While pairwise sequence identity is not a universally dependable measure of phylogenetic information content, these values illustrates that the sequences within a QuartOP are neither identical to one another, nor so divergent as to be saturated with substitutions and of questionable homology [ 30 ] . Using only the most conserved QuartOPs does not change the qualitative result: each of the three possible tree topologies is supported by about an equal number of QuartOPs (see supplementary material).
Thus, similar inclusions were observed when Rab24 was expressed with substitutions at the N/T position; i.e. , T120A (Fig.
However, since coat protein is a symmetric homodimer, substitutions are necessarily introduced simultaneously into both halves of the molecule, making it difficult to distinguish the separate effects of mutations on binding of different halves of the asymmetric RNA ligand.
In Ec-MoeB, β sheet 5 (residues 149-155 of Ec-MoeB, Figure 3) forms part of the pocket which accepts the C-terminal portion of MoaD, of which the terminal glycine is subsequently adenylated [ 7 ] . Ec-MoeB I155, located at the C-terminal end of this beta loop, is substituted in MoeBR proteins by Y and in MoeZ proteins by F or Y. These bulky substitutions may restrict access of the C-terminus of MoeD-like proteins and may indicate that a different type of substrate is adenylated by MoeBR and MoeZ.
It is known from experimental studies that nucleotide substitutions at highly diverse positions influence recombination efficiency [ 46, 52].
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