Words similar to substitutions

Example sentences for: substitutions

How can you use “substitutions” in a sentence? Here are some example sentences to help you improve your vocabulary:

It is noteworthy that in this region of the gene, each of the nucleotide substitutions results in an amino acid replacement.
Such substitutions have previously been observed in other papain-like peptidases with the serine participating in a functional active site [ 61, 62].
To investigate further whether the three sets of substitutions affect the ability of Boi1-PH to bind these lipids, we used the vesicle co-sedimentation assay.
Amino acid substitutions in the N(T)KxD motif cause a drastic reduction in the affinity of Ras-related GTPases for guanine nucleotides [ 35 36 ] . When overexpressed in cultured cells, these mutant GTPases function as dominant-suppressors of their endogenous counterparts [ 26 27 31 ] , presumably because they can compete for interaction with effectors, exchange factors or docking proteins, but cannot cycle on and off membranes in a nucleotide-dependent manner.
In the prefrontal cortex, the breakdown of synaptic dopamine through the COMT pathway is more critical since PFC is characterized by greater extracellular diffusion & slower clearance of dopamine than elsewhere in the brain [ 53 ] . The most widely examined polymorphisms in COMT were identified by Lachman [ 54 ] who found a G-to-A change at codons 108 and 158 of the COMT gene, resulting in Valine-to-Methionine substitutions which account for 3- to 4-fold differences in COMT activity in red blood cells and liver.