Words similar to substrates

Example sentences for: substrates

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Histidine triad (HIT) enzymes are a superfamily of nucleotide hydrolases and transferases that contain a catalytic motif related to the sequence HisφHisφHisφφ (where φ represents a hydrophobic amino acid) and act on substrates containing a nucleoside monophosphate [ 24].
Furthermore, the DNA polymerase active site in permeabilized core particles is accessible to the exogenous RNAseH substrates (Fig.
Mutagenesis [ 14 ] , X-ray crystallography [ 16 40 ] , and stereochemical analysis [ 41 ] indicate that His96 is the nucleophile that attacks the α-phosphate of Fhit substrates.
This putative autoregulatory mechanism for the catalytic subunit may help to explain why the overall abundance of PP1 during the various phases of the cell cycle remains relatively constant [ 32 ] . Historically, regulation of PP1 catalytic activity has resulted from associated subunits inhibiting or targeting the catalytic subunit towards substrates [ 33 ] . While the PP1 catalytic subunit is not found alone in the cell, such unassociated catalytic subunits have been shown to be active, at least in vitro . Although speculative, there may be a threshold amount of catalytic subunit in vivo above which associated proteins are limiting.
42] can be used to introduce viral vectors carrying genes encoding an activated form of PI3K, AKT, or candidate substrates for AKT into the mammary tissue of Wnt-1 TG mice.