Example sentences for: proteasomal

How can you use “proteasomal” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In humans the SWIRM domain is found linked to a JAB1/PAD1 catalytic domain, suggesting that this protein may serve as a link in the regulation of chromatinic proteins through proteasomal degradation.

  • The work reported here represents our major efforts during the past several years to follow a novel concept of proteasomal degradation in TGF-β/BMP signaling based upon the yeast two-hybrid data obtained in 1996.

  • In a separate study, we have shown that Az and HsN3 play targeting roles in the proteasomal degradation of Smad1 upon the activation of BMP type I receptors [ 39 ] . The observed proteasomal degradation of Smad1 upon the activation of BMP signaling could simply serve to irreversibly terminate Smad1-mediated signaling pathways of BMPs.

  • This is true of the transcription factor Cubitus interruptus (Ci): it is cleaved and its C-terminal portion is degraded [ 25 ] [ 26 ] [ 27 ] . Cleavage and degradation require phosphorylation, SCF Slmb, and proteasomal activity.

  • This interaction was suggested to play a role in Tax-induced proteasomal processing of the P105 subunit of NF-κB [ 32 ] . Other proteasome integral components, especially those in the 19S regulator of the 26S proteasome, have also been shown to bring proteins to proteasome for degradation [ 21 ] . Here we identified a unique role of HsN3 in the Az-involved targeting pathway that is coupled to BMP type I receptor activation.


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