Example sentences for: protml

How can you use “protml” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Alternative topologies were compared either directly, using the ProtML program, or were subjected to local rearrangement first.

  • Pairwise evolutionary distances between the sequences in concatenated alignments were calculated using the Dayhoff PAM model as implemented in the PROTDIST program of the PHYLIP package [ 44 ] . A distance tree was constructed from the resulting distance matrix by using the least-square [ 46 ] method as implemented in the FITCH program of PHYLIP [ 44 ] . The maximum likelihood tree was constructed with the JTT-F model of amino acid substitutions [ 47 ] , as implemented in the ProtML program of the MOLPHY package [ 48 ] , by optimizing the least squares tree with local rearrangements.

  • The statistical significance of various nodes of this ML tree was assessed using the relative estimate of logarithmic likelihood bootstrap (Protml RELL-BP) with 10,000 replicates.

  • Briefly, this process involved the construction of a least-squares tree using the FITCH program or a neighbor-joining tree using the NEIGHBOR program (both from the Phylip package) [ 38], followed by local rearrangement using the Protml program of the Molphy package [ 37] to arrive at the maximum likelihood (ML) tree.

  • Alternative topologies were created manually by modifications of the original tree and directly compared by ProtML.


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