Words similar to prothrombin
Example sentences for: prothrombin
How can you use “prothrombin” in a sentence? Here are some example sentences to help you improve your vocabulary:
However, despite association of the factor V G1691A (factor V Leiden) and prothrombin (factor II) G20210A mutations with venous thromboembolism and myocardial infarction [ 10 11 ] , neither mutation is strongly associated with risk of stroke [ 12 13 14 15 16 17 18 ] . Although a study of British adults found elevated levels of serum homocysteine to be associated with an increased risk of stroke [ 19 ] , a case-control study of a common polymorphism (methylenetetrahydrofolate reductase [MTHFR] T677C) that results in increased serum homocysteine concentrations found no difference between patients with stroke and controls in either genotype or allele frequency [ 20 ] . Because antiplatelet agents with different mechanisms of action can bring about significant reductions in stroke risk, several platelet receptor genes have been tested as candidate stroke susceptibility genes [ 21 22 ] . To date, however, no compelling evidence for an association between any platelet receptor gene polymorphism and risk of stroke has been found.
However, documented genetic risk factors, such as abnormalities in lupus anticoagulant, anti-thrombin III, proteins C and S, plasma homocysteine, anticardiolipin, β2 glycoprotein antibody, and prothrombotic mutations in Factor V and prothrombin were excluded.
The following information is recorded on the case report forms: patient history, physical examination, CT or MR of the head, white blood cell count, platelet count, and hemoglobin concentration, casual or fasting blood glucose, prothrombin time, and activated partial thromboplastin time, vital signs (height, weight, blood pressure, and temperature), international normalized ratio, lipid profile, plasma homocysteine concentration, and size and location of the symptomatic cerebral infarct as seen on head imaging.
Probes for the Factor II prothrombin (FII) mutant and normal alleles (see Table 1) were designed as discussed in Methods.
Disseminated intravascular coagulation (DIC) was defined as a positive D-dimer or elevated fibrin degradation products plus a falling platelet count of 25% of less of baseline, and elevation of either prothrombin time or partial prothrombin time, or clinical evidence of bleeding.
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