Words similar to prothrombin
Example sentences for: prothrombin
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However, despite association of the factor V G1691A (factor V Leiden) and prothrombin (factor II) G20210A mutations with venous thromboembolism and myocardial infarction [ 10 11 ] , neither mutation is strongly associated with risk of stroke [ 12 13 14 15 16 17 18 ] . Although a study of British adults found elevated levels of serum homocysteine to be associated with an increased risk of stroke [ 19 ] , a case-control study of a common polymorphism (methylenetetrahydrofolate reductase [MTHFR] T677C) that results in increased serum homocysteine concentrations found no difference between patients with stroke and controls in either genotype or allele frequency [ 20 ] . Because antiplatelet agents with different mechanisms of action can bring about significant reductions in stroke risk, several platelet receptor genes have been tested as candidate stroke susceptibility genes [ 21 22 ] . To date, however, no compelling evidence for an association between any platelet receptor gene polymorphism and risk of stroke has been found.
Presence of any of the following seven features, without an alternative cause, was required for satisfaction of the confirmatory criteria: ratio of partial arterial oxygen tension to inspired fractional oxygen below 280 (intubated) or 40% face mask in use (nonintubated); arterial pH below 7.30; urine output below 30 ml/h; systolic blood pressure below 90 mmHg or a fall in systolic blood pressure by more than 40 mmHg sustained for 2 hours despite fluid challenge; systemic vascular resistance below 800 dynes·s/cm 5; prothrombin time or partial thromboplastin time greater than normal or platelets below 100.
(6) Sepsis syndrome with disseminated intravascular coagulopathy (DIC) or coagulopathy required sepsis as defined in Appendix A in nosocomial events and DIC/coagulopathy defined as a drop in platelet count by 25% from baseline and an increase in prothrombin time (PT) or presence of fibrin degradation products.
Disseminated intravascular coagulation (DIC) was defined as a positive D-dimer or elevated fibrin degradation products plus a falling platelet count of 25% of less of baseline, and elevation of either prothrombin time or partial prothrombin time, or clinical evidence of bleeding.
Likewise, we found that preoperative prothrombin time was significantly ( P = 0.025) higher in the nonsurviving patients versus the surviving patients who required postoperative critical care utilization, and preoperative albumin was nearly significantly ( P = 0.056) lower in the nonsurviving patients versus the surviving patients who required postoperative critical care utilization.
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