Words similar to proteasome-mediated

Example sentences for: proteasome-mediated

How can you use “proteasome-mediated” in a sentence? Here are some example sentences to help you improve your vocabulary:

Characterization of these interactors reveals an unexpected physical and functional link between Smad1 and the proteasome-mediated degradation pathways.
Nonetheless, E2F is inactivated and/or downregulated upon progression to S phase, a regulatory feature that appears critical as E2F overexpression or ectopic activation induces apoptosis both in mammalian cells and in flies [ 12 ] [ 13 ] [ 14 ] [ 15 ] . Inactivation of the DNA-binding activity of E2F-1 by the cyclin A/Cdk complex has been shown to be critical for proper S phase progression [ 16 ] . In mammalian cells, E2F-1 is also subject to proteasome-mediated degradation [ 17 ] [ 18 ] [ 19 ] and recent evidence indicates that E2F-1 degradation occurs in S phase [ 20 ] . Control of E2F-1 stability has also been linked to its association with the F-box protein Skp2 [ 20 ] but this has not been tied to a specific phase of the cell cycle.
The isolation of Smad1 interacting proteins reveals a physical interaction between Smad1 and components in proteasome-mediated degradation pathways
However, additional data are clearly needed to further investigate the roles of calpain proteolysis and proteasome-mediated proteolysis on chromosome segregation as well as the numerous other potential molecular mechanisms of aneuploidy.
An increasing body of evidence indicates that targeted 26S proteasome-mediated proteolysis of transcription factors is an integral part of the transactivation process.