Words similar to proteasome

Example sentences for: proteasome

How can you use “proteasome” in a sentence? Here are some example sentences to help you improve your vocabulary:

The first construct contains a Flag-epitope placed at the C-terminus of HsN3 (N3-F), since the C-terminus of HsN3 is not buried inside of the mature proteasome, according to the crystal structure of HsN3 [ 38 ] . The second and the third constructs contain either the Flag or the T7 epitopes placed at the N-terminus of HsN3 (F-ΔN3, T7-ΔN3).
Indeed, treatment of the macrophages with the proteasome inhibitor MG132, which prevents NF-κB activation [33], abrogated endotoxin-induced activation of resistin expression (data not shown).
With so many proteins to target for degradation, the activity of the proteasome is subject to multiple levels of regulation.
In the overwhelming majority of cases, selected proteins are first “labeled” by the addition of several copies of a small protein tag called ubiquitin and are thus targeted for degradation in the proteasome (Figure 1).
The proteasome assembly intermediates could be a site for the entry of substrates into the degradation chamber via an unfold-trap mechanism that is coupled to the final maturation of the 20S proteasome.