Example sentences for: proteasome

How can you use “proteasome” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In a separate study, we demonstrated that Smad1 is targeted to proteasome for degradation, a process involving the co-targeting role of Az and HsN3 [ 39 ] . Here we showed that SNIP1, after being recruited to Az, is targeted, together with Smad1, to proteasome for degradation.

  • Furthermore, an integral component of proteasome, HsN3 [ 22 23 24 ] , which is a β subunit of the 20S catalytic core, was also isolated as a strong and specific Smad1 interactor.

  • In the overwhelming majority of cases, selected proteins are first “labeled” by the addition of several copies of a small protein tag called ubiquitin and are thus targeted for degradation in the proteasome (Figure 1).

  • This depletion is due to the selective targeting of TBP and TAF II 135 for proteolytic degradation since depletion is blocked when cells are treated with proteasome inhibitors.

  • Cells were lysed in lysis buffer (20 mM HEPES, pH 7.4, containing 100 mM NaCl, 5 mM MgCl 2 , 5 mM EDTA, 0.5% Triton X-100 and 1 mM PMSF) with 1 × proteasome inhibitor cocktail (Boehringer Mannhein).


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