Words similar to proteasome
Example sentences for: proteasome
How can you use “proteasome” in a sentence? Here are some example sentences to help you improve your vocabulary:
To test the hypothesis that transient inhibition of proteasomal activity during mouse meiosis I was associated with chromosome missegregation, mouse oocytes were exposed in vitro to the reversible proteasome inhibitor MG-132 and metaphase II (MII) oocytes were analyzed for structural and numerical chromosome aberrations.
While SCF triggers ubiquitination and proteasome action degrades many substrates to completion, a few targets are instead cleaved and partially degraded.
This system employs a cascade of enzymatic reactions that covalently attach a ubiquitin chain to substrate proteins, thereby targeting them to the proteasome [ 19 ] . The ubiquitin transfer reaction involves three enzymes: E1, which mediates the ATP-dependent activation of ubiquitin, and E2, or ubiquitin conjugating enzyme (UBC), which, together with an E3 ubiquitin ligase, transfers ubiquitin to the target protein.
These data indicate that Az has a more general role in targeting different substrates to proteasome for degradation.
The incomplete rescue of SNIP1 level by lactacystin suggests the involvement of additional mechanisms other than 26S proteasome in SNIP1 degradation.