Example sentences for: proteasome

How can you use “proteasome” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Our data suggests that Smad1 and Az both interact with HsN3 only before HsN3 is fully incorporated into the mature 20S proteasome.

  • In fact, p27 depletion in several cancers was shown to result from increased proteolysis via the ubiquitin/proteasome system [ 15 16 17 18 ] .

  • HsN3 may simply bring the Smad/Az containing complex close enough to the 26S proteasome and then delivers it to the 19S complex via Az interaction with its receptor within 19S regulator.

  • As one of the seven β subunits of the 20S proteasome, the newly translated HsN3 has an N-terminal 44 amino-acid prosequence, which is processed upon the complete assembly of HsN3 into the mature 20S proteasome [ 22 23 24 ] . The assembly of the 20S proteasome involves multiple steps and the formation of assembly intermediates [ 33 34 35 36 ] . As illustrated in Fig.

  • This metalloprotease-like activity maps to the putative catalytic MPN+/JAMM motif of the lid subunit Rpn11 and lies at the heart of proteasome mechanism by linking deubiquitination with protein degradation.


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