Words similar to proteasome
Example sentences for: proteasome
How can you use “proteasome” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the overwhelming majority of cases, selected proteins are first “labeled” by the addition of several copies of a small protein tag called ubiquitin and are thus targeted for degradation in the proteasome (Figure 1).
The lack of strong signals of Smad1 or Smad4 in the immunoprecipitates of SNIP1 in the presence of BMP type I receptor activation may be due to the transient nature of the complex, which, as shown below, is targeted to proteasome for degradation.
Further, a mutant of Siah1a was constructed with the RING finger domain deleted, such that the protein was unable to act in the ubiquitin/proteasome pathway [ 46 ] . This deletion construct was as effective in attenuating group I mGluR function as the wild type Siah1a, providing supporting evidence that the effect of Siah1a resulted from its physical association with the receptors, rather than through a resulting reduction in receptor expression levels.
0 mcg/ml MG-132 increased the frequency of MI arrested oocytes, this cell-cycle retardation may not be entirely attributed to proteasome inhibition.
Besides inhibiting proteasome activity, the peptide aldehyde proteasome inhibitors have been also reported to repress certain lysosomal cysteine proteases and calpains [ 49 ] . The finding that MG-132 can obstruct the casein degrading activity of the calcium-dependent protease calpain [ 50 ] appears relevant to oocyte maturation.