Example sentences for: proliferation

How can you use “proliferation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several genes associated with cell growth and proliferation were up-regulated in UC—a finding similar to previous microarray studies that had reported involvement of cancer-related genes in IBD (although the altered genes were different).

  • The differentiative and anti-mitotic actions of C/EBPα have been observed in a variety of cell culture models [ 23 24 26 40 53 ] . To date, studies of the C/EBPα block of proliferation have relied on comparing the growth [ 23 24 25 40 ] or DNA synthetic [ 22 24 25 26 27 ] rates of C/EBPα-expressing and non-expressing cells.

  • This represents an increased AP production per cell, because BMP2 had no effect on BMPC proliferation over 5 days (data not shown).

  • Such an effect would be consistent with the accumulation of immature, proliferating chondrocytes in Hoxc-8 transgenetic mice [ 1 ] . We therefore characterized cell proliferation in Hoxc-8 transgenic chondrocytes.

  • Signaling by the IGF-IR has been studied in many different cell types and is important for proliferation, survival, motility, adhesion, transformation, tumor formation and metastasis [for reviews see refs [ 31 32 ] ]. The receptor can directly phosphorylate the insulin receptor substrate 1 (IRS-1) and Shc proteins in the intact cell causing activation of PI-3Kinase and ras signaling [ 33 ] . More recently, it has been shown that the IGF-IR signals via the Gβγ subunits of the heterotrimeric Gi complex to stimulate PI-3Kinase and ras, and also activates the JAK/Stat pathway to cause phosphorylation of Stat3 [ 34 35 ] .


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