Words similar to proliferate
Example sentences for: proliferate
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The answer, of course, is increasing returns: To proliferate varieties (and hence to produce each variety at a smaller scale) means to increase costs.
Note that T cells from proteoglycan-immunized CD28-deficient mice proliferate in response to proteoglycan stimulation, albeit at a rate lower than that in wild-type T cells (Fig.
However, CD28-deficient T cells from proteoglycan-immunized animals can proliferate in response to proteoglycan stimulation in vitro , albeit at a rate lower than that in wild-type T cells, which is consistent with the report by Oliveira-dos-Santos et al . [ 30 ] . It has been demonstrated that, in the absence of CD28 engagement, T cells require very high TCR occupancy and prolonged stimulation, whereas CD28 costimulation allows T cells to respond to lower degrees of TCR occupancy [ 30 31 ] . In support of this observation, CD28 -/-mice can still mount immune responses, which vary in magnitude and efficiency depending on the antigen or infectious agent [ 30 32 ] . Our results and those reported by others [ 30 ] suggest that CD28 may regulate the threshold for T-cell activation.
The processes of arterial remodeling involve regulation of vascular cell dynamics and control of matrix synthesis and degradation [ 1 ] . Endothelial cell (EC) proliferation is observed in flow-induced arterial dilation [ 2 ] and in vessel luminal expansion in mesenteric arterial collaterals in the rat [ 3 ] . Smooth muscle cells (SMC) have also been shown to proliferate in the vessel dilatation remodeling [ 3 ] . In the meantime, extracellular matrix (ECM) is involved in a variety of remodeling processes [ 4 5 6 7 8 9 ] including flow-induced arterial dilation [ 10 ] . These observations indicate that cell proliferation and ECM accumulation are critically involved in vessel remodeling.
This was regardless of levels of expression of the Hoxc-8 transgene (Figure 7, Panel B) which increases with increasing transgene dosage [ 1 23 ] . These data indicate that, after appropriate time in culture, transgenic chondrocytes were able to proliferate normally, at least over the 24 hours duration of the assay.