Words similar to proliferating
Example sentences for: proliferating
How can you use “proliferating” in a sentence? Here are some example sentences to help you improve your vocabulary:
In the present system, NGF converts proliferating PC12 cells to a non-proliferating neuronally differentiated state.
The proximal 5' flank of the FGFR1 gene has a similar clustering of SP-1, Mef2, and SRF sites [ 36 ] . The FGFR1 gene is expressed in terminally differentiated muscle, although at a lower level than in proliferating myoblasts [ 36 ] . The expression depends on Sp-1 sites in the proximal promoter and the binding of Sp-1 and Sp-3 to these sites.
Previously, we [ 1 ] found that upon overexpression of Hoxc-8, the vertebral cartilages accumulate immature chondrocytes, and we showed that these cells are proliferating cells by virtue of staining for Proliferating Cell Nuclear Antigen (PCNA).
For instance, they are dispensable for DNA damage-dependent activation of the Rad26/Rad3-kinase complex [ 18 ] , but are required for the Rad3-dependent phosphorylation of Chk1 [ 23 ] . Structural predictions of Hus1, Rad1 and Rad9 have led to the proposal that all three fold similarly to the subunits of Proliferating Cell Nuclear Antigen (PCNA) [ 24 25 26 ] . Consistent with these predictions, PCNA exists as a homotrimer [ 27 ] while Hus1, Rad1 and Rad9 all interact and possibly form a heterotrimer [ 25 28 ] . In addition, Rad17 has sequence similarity and physical interactions with subunits of Replication Factor C (RFC) [ 29 30 ] . Based on the RFC-PCNA paradigm, the Rad17-RFC complex may load the PCNA-like Rad9-Rad1-Hus1 (9-1-1) complex onto genomic lesions discovered by the Rad26/Rad3 complex.
A priori, one might expect that most cell cycle related genes will be less expressed in growth arrested, confluent, or G 0 cells relative to proliferating cultures due to a generalized decrease in metabolic activity, cell protein content, and cell size.
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