Words similar to proliferating
Example sentences for: proliferating
How can you use “proliferating” in a sentence? Here are some example sentences to help you improve your vocabulary:
For instance, they are dispensable for DNA damage-dependent activation of the Rad26/Rad3-kinase complex [ 18 ] , but are required for the Rad3-dependent phosphorylation of Chk1 [ 23 ] . Structural predictions of Hus1, Rad1 and Rad9 have led to the proposal that all three fold similarly to the subunits of Proliferating Cell Nuclear Antigen (PCNA) [ 24 25 26 ] . Consistent with these predictions, PCNA exists as a homotrimer [ 27 ] while Hus1, Rad1 and Rad9 all interact and possibly form a heterotrimer [ 25 28 ] . In addition, Rad17 has sequence similarity and physical interactions with subunits of Replication Factor C (RFC) [ 29 30 ] . Based on the RFC-PCNA paradigm, the Rad17-RFC complex may load the PCNA-like Rad9-Rad1-Hus1 (9-1-1) complex onto genomic lesions discovered by the Rad26/Rad3 complex.
Replication-defective adenoviral vectors offer several advantages that make them attractive for gene delivery [ 3 4 5 6 ] . Adenoviral vectors are able to transduce proliferating or quiescent cells; they can accommodate dual, large insert sizes and can deliver additional genes by superinfection; and stable, high-titer viral stocks are easily generated [ 7 ] . Further, since the adenoviral genome is maintained extra-chromosomally, insertion site-dependent effects of the host genome are minimized, and exogenous genes can be reliably expressed at high levels.
The protein is frequently expressed throughout the cell cycle of proliferating cells, and it has not been detected in non-proliferating cells.
Hierarchical cluster analysis of these experiments clearly showed the distinct differences in transcriptional profiles between AIS-derived and normal male fibroblasts and between proliferating and normal fibroblasts (Figure 3).
However, accumulation of proliferating cells can also result from a slow-down of the cell cycle, in form of a lower rate of BrdU incorporation.
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