Example sentences for: proliferative

How can you use “proliferative” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Infection of cultured podocytes with replication incompetent HIV-1 demonstrated that HIV-1 gene expression leads to the proliferation and dedifferentiation of the infected podocytes [ 6 7 8 ] , recapitulating the phenotypes observed in HIVAN specimens [ 9 10 ] . Similarly, renal expression of replication incompetent HIV-1 proviral transgenes in mice and rats produces a proliferative renal lesion that is indistiguisable both histopathologically and clinically from human HIVAN [ 11 12 13 14 ] . These observations raise the possibility that HIV-1 gene products may interact with mitogenic pathways in infected renal epithelium to cause aberrant cell-cycle engagement.

  • In order to be classified as an epitope, the average proliferative response to a peptide had to reach a stimulation index of 3.0.

  • Tight glycemic control can slow the progression of diabetic retinopathy (Figures 1–3) [9] and help prevent development of proliferative diabetic retinopathy.

  • Upregulation might engage a feedback loop mechanism, in which Notch activation in neighboring cells maintains them in a proliferative, unspecified state whereas those cells that upregulate Delta expression, and have decreased Notch activity, are driven to exit the cell cycle and to differentiate.

  • Consistent with this hypothesis was the prior finding that early antiretroviral therapy led to induction of HIV-specific proliferative responses similar to those that had been observed in patients with long-term, non-progressing HIV [2].


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