Example sentences for: proline

How can you use “proline” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine the effect of CPT on newly synthesized collagenous proteins, we used an established method of metabolic labeling with [ 3H]proline followed by SDS-PAGE electrophoresis [ 22].

  • Repetitive proline sequences tend to adopt a polyproline II (PPII) helix, consisting of an extended structure with three residues per turn.

  • In the analysis of amino-acid positions, glycine, proline and tyrosine were found to be the most conserved residues in TM-helical regions, whereas isoleucine, valine, methionine and threonine were identified as the least conserved residues, relative to average occurrence.

  • Among these are that glycine, tyrosine, and proline appear frequently in conserved locations within family transmembrane helices and that the specific pair motifs are found in families that seem to be transporters, symporters, and channels.

  • Interestingly, in the other study, the authors found that deletion of a proline-rich sequence corresponding to sα i2 amino acids 348-359 (Figure 1) changed localization of sα i2 from Golgi membranes to a more diffuse localization throughout intracellular membranes [ 4 ] . However, mutation of proline residues to alanines failed to affect sα i2 localization [ 4 ] . Thus, little evidence exists to support a specific membrane targeting role for the novel sα i2 sequence.


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