Words similar to prb
Example sentences for: prb
How can you use “prb” in a sentence? Here are some example sentences to help you improve your vocabulary:
Using this technique, they showed a G1 block by PP1 that was dependent upon the presence of pRB.
A proposed mechanism of SAHA stresses the involvement of pRb2/p130-E2F-4 interaction and nuclear localization, which ultimately results in cell growth arrest and repression in nuclear E2F-1 and PCNA protein levels, and the subsequent inhibition of DNA synthesis in both cell lines.
pRB phosphorylation varies as a function of cell cycle phase; during G 1 the hypophosphorylated form predominates, while the hyperphosphorylated form accumulates during S, G 2 and M phase [ 14 15 16 ] . It is this hypophosphorylated form of pRB present during early and mid G 1 which functions to modify gene expression.
10) were mouse monoclonal antibodies to cyclin D1 (cD1, clone DCS-6, diluted 1:20, NeoMarkers, Fremont, CA), cyclin E (cE, HE111, 1:40, Santa Cruz Biotechnology, Santa Cruz, CA), Ki67 (Ki-67, 1:50, Dako Corporation, Carpinteria, CA), p21 Cip1/WAF1(p21, clone 70, 1:25, Transduction Laboratories, San Diego, CA), and retinoblastoma protein (pRb, 05-218, 1:50, Upstate Biotechnology, Lake Placid, NY).
Immunostaining analysis using monoclonal antibody specific for pRb2/p130 revealed that SAHA enhanced pRb2/ p130 nuclear localization in both cell lines treated with SAHA for 24 h compared with their controls (Fig.
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