Example sentences for: prb

How can you use “prb” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Protein (250 μg) from the control-infected or HIV-1-infected podocytes on day 14 of the differentiation protocol was also analyzed by western blot for total pRb (ECL detection of a 1:1000 dilution of rabbit anti-Rb, Santa Cruz Biotechnology) and phospho-Rb (Ser780) (ECL detection of a 1:500 dilution of rabbit anti-phospho-Rb (Ser780) antibody binding, Cell Signaling).

  • The difference in the level of hypophosphorylated pRb pocket protein isoforms between the two cell lines treated with SAHA may be attributed to differences in G1 and S phase cdk activity (examined in the following section).

  • SAHA also resulted in the inhibition of G1/S kinase activities and, consequently, hypophosphorylation of the three pRb pocket proteins, which led to G1 cell growth arrest and dramatic decreases in DNA synthesis in both cell lines.

  • 5) and its nuclear localization after SAHA treatment was associated with interaction to E2F-4, equal amounts of nuclear protein extracts were immunoprecipitated with antibodies against E2F-4 followed by western blot analysis against pRb2/p130 antibodies.

  • Figure 6shows a significant decrease in the 32P radiolabel intensity for pRB following incubation with the anti-hemagglutinin immunoprecipitate compared to the normal mouse IgG control immunoprecipitate.


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