Example sentences for: polyubiquitylation

How can you use “polyubiquitylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • To determine whether Pcu3p is associated with such an activity and how it is affected by CSN, we developed a substrate-independent in vitro polyubiquitylation assay, similar to that originally reported by Lyapina et al.

  • A heterooligomeric SCF Pop1p-Pop2pcomplex mediates polyubiquitylation of phosphorylated Rum1p.

  • Thus, CSN deficiency appears to stimulate Pcu3p-associated ubiquitin ligase activity in vitro . A similar stimulation was obtained for substrate-specific polyubiquitylation of phosphorylated Rum1p by SCF Poppurified from csn5 mutants (unpublished observation).

  • The experiment demonstrated that Pop1p and Pop2p each associate with polyubiquitylation activity even in the absence of their respective heterooligomerizing F-box proteins (Fig.

  • Taken together these results strongly suggest that SCF Pop1p-Pop2pmediates the polyubiquitylation of CDK phosphorylated Rum1p in vitro .


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