Words similar to polyubiquitylation

Example sentences for: polyubiquitylation

How can you use “polyubiquitylation” in a sentence? Here are some example sentences to help you improve your vocabulary:

Pcu3p-Myc complexes isolated from pcu3-13myc cells did not show any recognizable polyubiquitylation activity above background with any of the seven UBCs tested (Fig.
Genetic experiments suggested that degradation of Rum1p depends on the Pop1p and Pop2p F-box proteins [ 18 20 ] , but also requires phosphorylation of Rum1p on serine 58 and threonine 62 by cyclin-dependent kinase (CDK) [ 21 ] . Thus, phosphorylated Rum1p may be a substrate for SCF Pop1p-Pop2p-mediated polyubiquitylation.
Given our ability to prepare immunopurified SCF Pop1p-Pop2pthat bound phosphorylated Rum1p, we sought to reconstitute Rum1p polyubiquitylation in vitro.
Taken together these results strongly suggest that SCF Pop1p-Pop2pmediates the polyubiquitylation of CDK phosphorylated Rum1p in vitro .
To determine whether Pcu3p is associated with such an activity and how it is affected by CSN, we developed a substrate-independent in vitro polyubiquitylation assay, similar to that originally reported by Lyapina et al.