Words similar to polytopic

Example sentences for: polytopic

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A complete list of assigned polytopic membrane domains
We identified families of polytopic membrane domains in Pfam [ 15] by allocating TM-helices annotated in SWISS-PROT [ 16] to proteins in Pfam.
However, it is unlikely that polytopic membrane domains in the 12-TM Pfam-A families have a structure like that of ABC transporters; as there is no obvious sequence similarity within the sequence containing the 12 TM-helices, it is unlikely to form two 6-TM-helical bundles.
Our results confirm these findings; in addition, we find that glycine and tyrosine are also highly conserved residues in polytopic TM-helices.
Therefore, classification of polytopic membrane domains into families gives us another way to look at the distribution and functions of integral membrane proteins in genomes.