Words similar to polyubiquitinated

Example sentences for: polyubiquitinated

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Once bound to the proteasome, a polyubiquitinated substrate can be unfolded by the RP and irreversibly translocated into the CP.
II 135 in extracts where ubiquitination of RARγ2 can be detected (our unpublished data), at early times we do observe a significant shift in the electrophoretic mobility of TAF II 135 which may correspond to a polyubiquitinated intermediate While the molecular events involved in degradation of transcription factors are in general poorly understood, it is noteworthy that both NRs and TBP have been reported to interact with the proteasome component SUG1 [ [ 60 61 ] ] which may act to target these proteins for degradation.
0 μg/mlMG-132 may be related to the sustained elevation of MPF activity noted in rat oocytes exposed to MG-132 [ 42 ] and the stabilization of polyubiquitinated proteins and enhanced deubiquitination of nucleosomal histones in chromatin following proteasomal inhibition [ 62 ] .
In the competition between proteolysis and deubiquitination, polyubiquitinated proteins rarely accumulate in the cytoplasm of “healthy” cells, as they are either irreversibly degraded or deubiquitinated and rescued.