Words similar to polyubiquitin

Example sentences for: polyubiquitin

How can you use “polyubiquitin” in a sentence? Here are some example sentences to help you improve your vocabulary:

The addition of a polyubiquitin chain to a protein requires the sequential action of a ubiquitin-activating enzyme (E1), a ubiquitin-conjugating enzyme (E2) and a ubiquitin-protein ligase (E3) [ 1 ] . E3 activities are thought to be essential because they are involved in substrate recognition.
Extended polyubiquitin chains could slow down chain disassembly, thereby allowing ample time for unfolding and proteolysis of the substrate (Figure 2).
It has been proposed that long polyubiquitin chains commit a substrate to unfolding and degradation by the proteasome, whereas short chains are poor substrates because they are edited by deubiquitinating enzymes, resulting in premature substrate release (Eytan et al.
The well-known ubiquitin-dependent pathway involves the covalent attachment of ubiquitin to substrate proteins to form polyubiquitin chain, which then targets the marked substrates to proteasome for degradation [ 17 19 20 ] . The ubiquitin-independent pathway is not well defined, but involves targeting proteins other than ubiquitin.
A base subcomplex of the RP is pivotal in anchoring polyubiquitin chains during this process, either directly or via auxiliary ubiquitin-binding proteins (Lam et al.