Words similar to polyubiquitin
Example sentences for: polyubiquitin
How can you use “polyubiquitin” in a sentence? Here are some example sentences to help you improve your vocabulary:
The well-known ubiquitin-dependent pathway involves the covalent attachment of ubiquitin to substrate proteins to form polyubiquitin chain, which then targets the marked substrates to proteasome for degradation [ 17 19 20 ] . The ubiquitin-independent pathway is not well defined, but involves targeting proteins other than ubiquitin.
As an outcome of this requirement, longer polyubiquitin tags would be preferential substrates for degradation by the proteasome.
Extended polyubiquitin chains could slow down chain disassembly, thereby allowing ample time for unfolding and proteolysis of the substrate (Figure 2).
Proteins are targeted for proteasome-mediated degradation by attachment of a polyubiquitin chain.
A base subcomplex of the RP is pivotal in anchoring polyubiquitin chains during this process, either directly or via auxiliary ubiquitin-binding proteins (Lam et al.