Words similar to pgi

Example sentences for: pgi

How can you use “pgi” in a sentence? Here are some example sentences to help you improve your vocabulary:

COX-2 activity was determined by measuring PGE 2 , 6-keto-PGF 1α (stable PGI 2 metabolite), TXB 2 (stable TXA 2 metabolite), and PGF 2α production in stimulated fibroblasts.
The ratio of PGI 2 to TXA 2 metabolites was lower in IPF fibroblasts at baseline and with IL-1β stimulation.
It is important to mention that our experiments were conducted at similar passage levels (passage 6 to 8) in both groups, since senescence of fibroblasts is associated with a shift from the biosynthesis of PGI 2 to TXA 2 [ 24 25 ] . It is possible that the difference seen in our study between HF-IPF and HF-NL could result from comparing fibroblasts of different ages.
We hypothesize that the lower PGI 2 :TXA 2 ratio seen in HF-IPF may be a phenotypic alteration that plays a role in the pathogenesis of IPF.
The above results suggest that a decreased PGI 2 :TXA 2 ratio could be a phenotypic alteration present in IPF fibroblasts, resulting in a loss of their capacity to autoregulate proliferation and extracellular matrix production.