Example sentences for: pgi

How can you use “pgi” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • Several LO non-essential gene products were critical ( pgi, pta, ackAB ) for growth within other phases.

  • COX-2 activity was determined by measuring PGE 2 , 6-keto-PGF 1α (stable PGI 2 metabolite), TXB 2 (stable TXA 2 metabolite), and PGF 2α production in stimulated fibroblasts.

  • The above results suggest that a decreased PGI 2 :TXA 2 ratio could be a phenotypic alteration present in IPF fibroblasts, resulting in a loss of their capacity to autoregulate proliferation and extracellular matrix production.

  • , PGE 2 , TXB 2 , and PGI 2 ), and antifibrogenic cytokines (e.g.

  • On the other hand, PGI 2 decreases vascular smooth muscle cell proliferation and collagen and glycosaminoglycane synthesis, via activation of adenylyl cyclase and subsequent production of cAMP [ 17 ] . Betaprost, an analog of PGI 2 , decreases procollagen I and III mRNA expression in cardiac fibroblasts [ 18 ] . These effects may counteract the profibrotic effects seen with TXA 2 and it is possible that an alteration of a "normal" physiologic balance between PGI 2 and TXA 2 could increase tendency towards fibrogenesis.

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