Words similar to pgia
Example sentences for: pgia
How can you use “pgia” in a sentence? Here are some example sentences to help you improve your vocabulary:
In induced models of autoimmunity, the CD28-B7 interaction has been shown to regulate disease susceptibility by rendering autoreactive T cells anergic, or alternatively by upregulating the threshold for autoreactive T-cell activation [ 30 ] . Furthermore, we previously showed that impaired Fas-mediated activation-induced cell death (AICD) of autoreactive T-helper-1 cells may be responsible for the development of PGIA [ 20 ] . Therefore, AICD and/or T-cell anergy, but not the CD4 +CD25 +regulatory T cells, may be responsible for deletion or inactivation of autoreactive T cells in autoimmune arthritis.
To further investigate whether the CD4 +CD25 +T cells play a role in PGIA, we performed adoptive transfer experiments using SCID mice as recipients.
No suppression of development of PGIA in SCID mice was observed.
To further evaluate the role of the CD4 +CD25 +cells in PGIA, an adoptive transfer system was employed.
This observation suggests that the CD4 +CD25 +regulatory T cells might not be involved in the development of PGIA.