Words similar to pgia

Example sentences for: pgia

How can you use “pgia” in a sentence? Here are some example sentences to help you improve your vocabulary:

However, we cannot completely exclude the possibility that 1-4 : 1 ratios may be required for suppression of PGIA.
This finding excludes the possibility that reduced expression of CTLA-4 in the CD4 +CD25 +regulatory T cells from BALB/c mice with PGIA may mediate the induction of the disease.
In induced models of autoimmunity, the CD28-B7 interaction has been shown to regulate disease susceptibility by rendering autoreactive T cells anergic, or alternatively by upregulating the threshold for autoreactive T-cell activation [ 30 ] . Furthermore, we previously showed that impaired Fas-mediated activation-induced cell death (AICD) of autoreactive T-helper-1 cells may be responsible for the development of PGIA [ 20 ] . Therefore, AICD and/or T-cell anergy, but not the CD4 +CD25 +regulatory T cells, may be responsible for deletion or inactivation of autoreactive T cells in autoimmune arthritis.
A controlled balance between initiation and downregulation of immune responses (peripheral tolerance) is important for maintaining immune homeostasis, whereas dysfunctional immune regulation may lead to chronic inflammation or autoimmunity [ 29 ] . The CD4 +CD25 +regulatory T cells have been shown to suppress autoimmunity in several animal models [ 2 ] . To evaluate the role of the CD4 +CD25 +regulatory T cells in PGIA, three approaches were used.
Our data suggest that the CD4 +CD25 +regulatory T cells might not be essential for controlling the development of PGIA.