Example sentences for: pgj

How can you use “pgj” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • 15d-PGJ 2 , 15-deoxy-delta 12, 14-Prostaglandin J 2 ; ERK, Extracellular signal-Regulated Kinase; 4-HNE, 4-hydroxynonenal, MAP kinases, Mitogen-Activated Protein kinases; MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide); PBS, phosphate-buffered saline; PPARs, peroxisome proliferator-activated receptors; RPE, retinal pigment epithelium.

  • While 15d-PGJ 2 is considered to be a PPARγ agonist, indomethacin and ibuprofen can activate both PPARγ and PPARα [ 27 ] . The following experiment was conducted to determine if a pure PPARα agonist, WY14643, could modulate the 25-OH-cholesterol induced cytotoxicity.

  • A combination of these two agents did not raise the viability above 15d-PGJ 2 alone (Fig.

  • Results indicated that 15d-PGJ 2 prevented H 2 O 2 induced cytotoxicity in primary human RPE cultures in a dose-dependent manner (Fig.

  • The rescue by 5 μM and 10 μM 15d-PGJ 2 was statistically significant (p < 0.001).


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