Example sentences for: pge
How can you use “pge” in a sentence? Here are some example sentences to help you improve your vocabulary:
One possible explanation for this apparent discrepancy is that although ERK1/2 are often involved in mitogenesis, in SMCs ERK activation can lead to inhibition of proliferation [ 46 ] . This occurs through ERK-mediated stimulation of PGE 2 production, which then inhibits the proliferation of SMCs [ 46 ] . Further experiments will determine whether RASMCs produce PGE 2 after treatment with III1-C.
Both PGE 2 and a cascade of proteolytic events that lead to extracellular matrix degradation have the potential for serving as paracrine regulators.
A plot of IL-1Ra concentration versus PGE 2 production of the IL-1Ra treated cells, relative to PGE 2 levels of control HSFs incubated with IL-1β alone, is shown in Fig.
In previous studies we have shown that the SLC/CCL21-mediated anti-tumor responses are accompanied by the enhanced elaboration of IFNγ, IP-10/CXCL10, MIG/CXCL9, GM-CSF and IL-12, but decreased PGE 2 , VEGF, IL-10, and TGF-β at the tumor site [ 9 10 ] . In addition, there was a marked increase in CD4 +and CD8 +cells secreting IFNγ and GM-CSF as well as DC expressing CD11c infiltrating the tumors.
Competition binding experiments revealed a rank order affinity consistent with an EP receptor: PGE 2 >> iloprost = PGD 2 = PGF 2α (Fig.