Words similar to pgc-

Example sentences for: pgc-

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Thus—through functional genomics—calcineurin, calmodulin-dependent kinase, PGC-1α, and activated PPARδ form the basis of a signaling network that controls skeletal muscle fiber-type transformation and metabolic profiles that protect against insulin resistance and obesity.
4-AP decreased production of cAMP (Figure 3A), and expression of StAR by PGC-2 (Figure 3B).
PGC-2 Cell Culture and Patch Clamp
The inhibitory action of 4-AP on progesterone production was investigated further using not only primary cultures, but also the spontaneously established granulosa cell line, PGC-2 [ 19 ] . Although PGC-2 lack FSH receptors, these cells can serve as a useful in vitro model for GC function, because they produce cAMP in response to forskolin and synthesize progesterone and estradiol when supplied with appropriate substrates.
Thereby, the combined results of experiments performed using PGC-2 and primary GC cultures suggest that 4-AP-inhibition of GC progesterone production may be linked to decreased expression of StAR, decreased generation of cAMP, and decreased output of estradiol.