Words similar to pgc-

Example sentences for: pgc-

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The pig granulosa cell line PGC-2 was obtained from Bruce Downey (McGill University) and maintained in culture in McCoy's modified 5A medium supplemented with 10% FBS, as described previously in detail [ 19 ] . PGC-2 cells have been well-characterized with respect to steroidogenic capability, cAMP response, and gonadotropin insensitivity [ 19 ] . Here, PGC-2 were seeded at a density of approximately 5 × 10 5cells/ml of serum-containing medium in 24-well tissue culture plates.
In contrast, 4-AP significantly reduced estradiol production by PGC-2 cultures provided with androstenedione (Figure 4B).
4-AP decreased production of cAMP (Figure 3A), and expression of StAR by PGC-2 (Figure 3B).
To this end, we treated primary cultures of GC and monolayers of the immortalized granulosa cell line PGC-2 [ 19 ] with the K +channel antagonist 4-aminopyridine (4-AP).
Thus—through functional genomics—calcineurin, calmodulin-dependent kinase, PGC-1α, and activated PPARδ form the basis of a signaling network that controls skeletal muscle fiber-type transformation and metabolic profiles that protect against insulin resistance and obesity.