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Example sentences for: pdi

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More than 75% (23/31) of the characterized genes within the top 50 genes in this cluster are localized to the ER and participate in various aspects of secretion, including protein folding ( KAR2, LHS1, FKB2, JEM1 ), protein disulfide isomerization ( EUG1, PDI1, ERO1 ), protein glycosylation ( GFA1, PMT3, PMI40, SEC59, WBP1, OST2 ), and forward and retrograde trafficking ( ERD2, ERP1, ERP2, SEC24, SEC13, RET2, RET3, and others [ 21]).
In contrast, sα i2 was not detected at plasma membranes, but instead typically displayed an intracellular and perinuclear staining pattern (Figure 2Band 2D), consistent with localization to intracellular membranes as previously described [ 3 4 ] . The subcellular localization of sα i2 showed overlap in immunofluorescent staining with the Golgi protein, β-COP (Figure 3Aand 3B) and the endoplasmic reticulum protein PDI (Figure 3Cand 3D); localization of sα i2 exclusively to Golgi was not observed, even at the lowest levels of detection.
The ability of mefloquine to upregulate the transcription of PDI, GRP78, GRP94 and calreticulin is consistent with this hypothesis.
Amplification products were separated by electrophoresis (at constant current of 25 mA) through 1.0% agarose gels in 0.5X TBE buffer, visualized and imaged using Nighthawk ™gel documentation system (pdi Inc., USA) after staining with ethidium bromide.
PDI has been identified in sea urchin eggs [ 45 ] , though localized only to the ER.