Words similar to pcna

Example sentences for: pcna

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Primary antibodies were obtained from commercial sources for detection of proliferating cell nuclear antigen (PCNA, Oncogene Science, Cambridge, MA) and actin (Sigma).
Polyclonal antibodies specific for CD4, CD8, γ/δ-TCR, TGF-β 1 , PDGF-A, PDGF-B, MCP-1 and polyclonal antibody to PCNA were purchased from Santa Cruz Biotechnology Inc., (Santa Cruz, CA).
For instance, they are dispensable for DNA damage-dependent activation of the Rad26/Rad3-kinase complex [ 18 ] , but are required for the Rad3-dependent phosphorylation of Chk1 [ 23 ] . Structural predictions of Hus1, Rad1 and Rad9 have led to the proposal that all three fold similarly to the subunits of Proliferating Cell Nuclear Antigen (PCNA) [ 24 25 26 ] . Consistent with these predictions, PCNA exists as a homotrimer [ 27 ] while Hus1, Rad1 and Rad9 all interact and possibly form a heterotrimer [ 25 28 ] . In addition, Rad17 has sequence similarity and physical interactions with subunits of Replication Factor C (RFC) [ 29 30 ] . Based on the RFC-PCNA paradigm, the Rad17-RFC complex may load the PCNA-like Rad9-Rad1-Hus1 (9-1-1) complex onto genomic lesions discovered by the Rad26/Rad3 complex.
The declining PCNA and GR reflect the sharp decline in cell proliferation and branching; the increasing BMP1 and BMP3b similarly reflects inhibition of cell proliferation (Fig.
The significant decline in PCNA transcript (Table 1) is consistent with the highly significant (p < 0.001) decline in PCNA-defined cell proliferation (Fig.