Example sentences for: pck

How can you use “pck” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Pck1 promoter can thus exist in altered states of cAMP responsiveness, depending on the transcription factors bound to CRU elements [ 55 ] . In hepatocytes, SREBP-1c can block transcriptional induction of cAMP on PEPCK-C metabolic action [ 56 ] .

  • Feeding of all three LC-PUFA diets led to an increase in hepatic Pck1 transcription, indicating gluconeogenesis was favored over glycolysis.

  • Phosphoenolpyruvate carboxykinase (Pck1) is the rate-limiting enzyme of gluconeogenesis, and most of its activity is regulated transcriptionally.

  • Overall, LC-PUFA may up regulate Pck1, the rate-limiting enzyme in gluconeogenesis, via cAMP-, SREBP-1- and/or PPAR-signaling [ 57 ] . This has the overall effect of limiting fat accumulation and shunting metabolic flux to gluconeogenesis.

  • Feeding of all three LC-PUFA diets led to an approximately 2* fold increase in hepatic Pck1 for each probe set identified.


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