Example sentences for: pck

How can you use “pck” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • The Pck1 promoter can thus exist in altered states of cAMP responsiveness, depending on the transcription factors bound to CRU elements [ 55 ] . In hepatocytes, SREBP-1c can block transcriptional induction of cAMP on PEPCK-C metabolic action [ 56 ] .

  • In the liver, cAMP regulates Pck1 transcription via the binding of CREB, as well as CCAAT/enhancer binding protein (C/EBP), to the CRU.

  • HNF3γ-signaling may regulate transcription of Pck1 (up regulated ca. 2* fold with each diet, presently), and G6pc (differentially regulated in the current experiment) [ 42 ] . HNF3γ is also reported to increase transcription of several genes that were not differentially regulated in the present experiment including, transferrin, tyrosine amino transferase [ 43 ] , and IPF-1/PDX-1 [ 40 ] .

  • Specifically, four probe sets with high sequence similarity to rat Pck1 (accession numbers AA106463, AA110781, AA080172, AA063800) demonstrated differential gene expression for the mouse Pck1 homologue.

  • Overall, LC-PUFA may up regulate Pck1, the rate-limiting enzyme in gluconeogenesis, via cAMP-, SREBP-1- and/or PPAR-signaling [ 57 ] . This has the overall effect of limiting fat accumulation and shunting metabolic flux to gluconeogenesis.


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