Example sentences for: pck

How can you use “pck” in a sentence? Here are some example sentences to help you improve your vocabulary:

  • In the liver, cAMP regulates Pck1 transcription via the binding of CREB, as well as CCAAT/enhancer binding protein (C/EBP), to the CRU.

  • Specifically, four probe sets with high sequence similarity to rat Pck1 (accession numbers AA106463, AA110781, AA080172, AA063800) demonstrated differential gene expression for the mouse Pck1 homologue.

  • Numerous hepatic genes containing SRE promoters were regulated by LC-PUFA in the present experiments, including SREBP-1 itself (consistent with [ 35 36 ] ). Also regulated were genes involved in triacylglycerol synthesis (Gpam), FA synthesis and elongation (Acas1, Acly, FA synthase, Spot14, Elovl2; Elovl2 may speculatively contain an SRE as described by Moon and colleagues [ 35 ] ), FA desaturation (Scd1), gluconeogenesis (Pck1), cytochrome p450 metabolism (Cyp4a-10 and -14), FA transport (Cd36), cholesterol metabolism and transport (Fpps), and ketone body formation (mitochondrial Hmgcs2).

  • The Pck1 promoter can thus exist in altered states of cAMP responsiveness, depending on the transcription factors bound to CRU elements [ 55 ] . In hepatocytes, SREBP-1c can block transcriptional induction of cAMP on PEPCK-C metabolic action [ 56 ] .

  • Phosphoenolpyruvate carboxykinase (Pck1) is the rate-limiting enzyme of gluconeogenesis, and most of its activity is regulated transcriptionally.


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