Words similar to npa

Example sentences for: npa

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The two largest were allelic with SEC23 and SEC13 , genes encoding known mediators of vesicular trafficking between the ER and Golgi [ 39 ] . The GFP-Nup mislocalization defects in the sec23 ( npa1 ) and sec13 ( npa2 ) mutants correlated with distinct ER membrane perturbations.
Although the npa/sec mutants characterized here are due to ER distortions, we predict that further analysis of the other npa mutants and GFP-based genetic strategies will significantly contribute to the effort of identifying factors required for NPC biogenesis.
The npa3/sec27 mutants displayed near wild-type invertase activity indicating that forward trafficking through the ER was not significantly disrupted.
Thus, the more rapid onset of growth arrest in npa1 and npa2 mutants suggested that the ts phenotype was not caused exclusively by a decrease in NPC number and nucleo-cytoplasmic transport capacity [ 23 35 ] and may be due to other cellular effects.
npa1-1 and npa2-1 cells ceased growing after 3-4 hours at the non-permissive temperature.