Words similar to npc

Example sentences for: npc

How can you use “npc” in a sentence? Here are some example sentences to help you improve your vocabulary:

We have used a genetic strategy to identify factors required for proper NPC biogenesis.
The results thus far indicate the screen is specifically enriched for NE/NPC specific effects versus nonspecific mutants that may affect GFP-Nup protein stability or levels (polymerases, transcription/translation factors, chaperones) (this report and unpublished results).
We predicted this sensitized background might further bias the screen toward mutations that perturb NPC structure.
Experiments using immuno-fluorescence in vertebrate cells are beginning to order the recruitment and timing of incorporation of individual nucleoporins during post-mitotic re-assembly [ 12 13 14 15 ] . Additionally, in vitro assembly studies with Xenopus egg or mitotic cell extracts have revealed several intermediates in NPC assembly and demonstrated a requirement for an intact double nuclear membrane prior to post-mitotic NPC assembly [ 16 17 18 19 ] . The modular nature of the NPC structure has also suggested that subcomplexes of discrete Nups may initially form and provide building blocks for biogenesis.
The approach is based on the ability to express functional GFP-nucleoporin fusions, and the assumption that NPC assembly/mislocalization mutants expressing a GFP-nucleoporin will have distinct fluorescence properties as compared to wild type cells.