Words similar to npc

Example sentences for: npc

How can you use “npc” in a sentence? Here are some example sentences to help you improve your vocabulary:

Mutants perturbing GFP-Nup localization could include cells with 1) NPC clusters in NE subregions, 2) mislocalization of the GFP-Nup or aggregated NPC subcomplexes to the cytoplasm or nucleus (due to either a block in new assembly or increased instability of existing NPCs), 3) mislocalization of the GFP-Nup due to indirect perturbation of the ER and NE membrane, or 4) decreased GFP-Nup incorporation followed by turnover resulting in cells with diminished total fluorescence.
One of our original predictions was that labeling multiple Nups with GFP would identify mutants with defects in the formation of the entire NPC structure.
The three dimensional structure of NPCs from both Xenopus and budding yeast Saccharomyces cerevisiae is characterized by distinct substructures that are arranged with an 8-fold rotational symmetry [ 3 ] . Eight spoke-like structures form the central NPC core and are flanked on the cytoplasmic and nuclear sides by ring structures.
NPC assembly is likely to be a highly regulated process that coordinates membrane fusion with the coincident assembly of peripheral nucleoporins.
Further analysis of mutant subgroups has revealed potential mechanisms for both direct and indirect perturbation of NPC assembly and localization, and indicates that this process requires multiple factors