Words similar to npc

Example sentences for: npc

How can you use “npc” in a sentence? Here are some example sentences to help you improve your vocabulary:

The initial isolation of multiple sec mutants from our screen that was designed to isolate mutants in NPC assembly and localization raised the question of whether any of the mutants were specific for defects in NPC assembly/structure.
This suggests that the mutagenesis was not saturating, and it is likely that mutations in additional genes that function in NPC biogenesis would be isolated by repeated application of this screening strategy.
NPC assembly is likely to be a highly regulated process that coordinates membrane fusion with the coincident assembly of peripheral nucleoporins.
A fraction of the total cellular Sec13p is isolated in a NPC subcomplex containing Nup84p, Nup85p, Nup120p, Nup145p-C, and Seh1p (a Sec13-related protein) [ 40 41 ] . Hurt and coworkers have also reported that ts sec13 mutants show enhanced growth defects when combined with a nup85Δ mutant, and result in the mislocalization of GFP-Nup49p to NE clusters and cytoplasmic foci [ 41 ] . This correlates with our observations of GFP-Nic96p and Nup170p-GFP in our sec13/npa2 mutant.
The phenotypes observed in sec13 and sec23 mutants might indicate that COPII vesicles and/or a vesicular biogenesis step is required for NPC formation; however, there are at least two indirect mechanisms by which NPC structure may be changed in these mutants.