Words similar to npc

Example sentences for: npc

How can you use “npc” in a sentence? Here are some example sentences to help you improve your vocabulary:

A fraction of the total cellular Sec13p is isolated in a NPC subcomplex containing Nup84p, Nup85p, Nup120p, Nup145p-C, and Seh1p (a Sec13-related protein) [ 40 41 ] . Hurt and coworkers have also reported that ts sec13 mutants show enhanced growth defects when combined with a nup85Δ mutant, and result in the mislocalization of GFP-Nup49p to NE clusters and cytoplasmic foci [ 41 ] . This correlates with our observations of GFP-Nic96p and Nup170p-GFP in our sec13/npa2 mutant.
Taken together, the work to date supports a framework wherein a network of in vivo interactions mediate NPC biogenesis, structural integrity, and proper localization in the NE.
We and others have focused on genetic analysis in the budding yeast S. cerevisiae to understand the mechanism of NPC biogenesis.
The results thus far indicate the screen is specifically enriched for NE/NPC specific effects versus nonspecific mutants that may affect GFP-Nup protein stability or levels (polymerases, transcription/translation factors, chaperones) (this report and unpublished results).
Second, we sought to preferentially isolate mutants that decrease overall NPC number versus inhibiting the incorporation of the single GFP-Nup.