Words similar to mitogen-activated
Example sentences for: mitogen-activated
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During this transition, tightly-regulated post-translational phosphorylation-dephosphorylation events and proteasome-mediated proteolytic reactions regulate the activation and inactivation of signal transduction pathways that control chromatin condensation, nuclear membrane dissolution, microtubule nucleation, and formation of a haploid oocyte [ 8 9 10 ] . Several kinases that exert major roles during OM include maturation promoting factor (MPF) [ 9 11 ] , mitogen-activated protein kinases (MAPKs) [ 12 13 ] , and the product of the c-mos protooncogene Mos kinase [ 14 15 ] . Also, during OM oocytes undergo two highly-regulated metaphase-anaphase transitions (MAT) in which homologous chromosomes are equally and randomly segregated to an oocyte and first polar body and a subsequent division in which equational division of sister chromatids results in a haploid oocyte and a second polar body.
Acute activation of the mitogen-activated protein kinase superfamily by TNFα and ceramide
In normal mitogen-activated cells eIF4E activity is enhanced due to elevated transcription of the eIF4E gene, a phosphorylation-dependent increase in affinity for the 7-methylguanosine cap, and phosphorylation-dependent inactivation of the inhibitor protein 4EBP.
Of interest to these studies are the three subfamilies within the mitogen-activated protein kinase (MAPK) superfamily including the extracellular signal-related kinases (ERKs), p38 and c-jun N-terminal kinases (JNKs) [ 31 ] . TNFα is one of many cytokines involved in luteal regression.
The mitogen-activated protein kinase (MAPK) family consists of three commonly recognized subgroups: the extracellular signal-regulated kinase (ERK), the c-jun-N-terminal kinase (JNK), also known as the stress activated protein kinase (SAPK) and the p38 kinase.