Words similar to mhck-a

Example sentences for: mhck-a

How can you use “mhck-a” in a sentence? Here are some example sentences to help you improve your vocabulary:

To gain insights into the relative cellular roles and localization of MHCK-A, MHCK-B, and MHCK-C, we have evaluated the behavior of GFP fusions corresponding to each of these enzymes.
Previously, Steimle and colleagues [ 23 ] reported that in interphase cells, during chemotaxis, random migration, and endocytic/phagocytic events, MHCK-A is recruited preferentially to anterior F-actin rich protrusions.
In previous work, when this method was applied to MHCK-A-expressing cell lines the elevated expression of MHCK-A resulted in myosin II hyperphosphorylation and myosin II filament disassembly, and corresponding loss of ability of cells to grow in suspension [ 24 ] . We observed the same effect in the current studies in attempting to force high expression of FLAG-MHCK-C.
This model is consistent with the recent report that MHCK-A displays enrichment into anterior F-actin-rich protrusions of polarized cells during chemotaxis, and into phagocytic and macropinocytotic extensions [ 23 ] . The polar localization of MHCK-A would be consistent with the long-standing "polar relaxation" model for cytoskeletal reorganization during cytokinesis [ 33 ] . MHCK-A may represent a factor that contributes to polar relaxation in this system via polar disassembly of myosin II filaments.
When the GFP fusions are imaged in myosin II null cells, both MHCK-A and MHCK-B display dynamics indistinguishable from their behaviour in cells wild type for myosin II.