Words similar to mhck-b

Example sentences for: mhck-b

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However, the strong similarity of MHCK-C to MHCK-A and MHCK-B in the conserved catalytic domain and the carboxyl-terminal WD repeat domain suggested that it might represent a third myosin heavy chain kinase in this organism.
To gain insights into the relative cellular roles and localization of MHCK-A, MHCK-B, and MHCK-C, we have evaluated the behavior of GFP fusions corresponding to each of these enzymes.
The cytosolic localization of MHCK-B suggests that this enzyme may contribute to a continuous and uniform turnover of myosin II filaments throughout the cell, although it is possible that MHCK-B plays more specific roles in functions yet to be identified.
Although MHCK-A has been extensively characterized at the biochemical level [ 18 22 25 31 ] , only limited biochemical analysis has been performed with bacterially-expressed subdomains of MHCK-B and MHCK-C [ 17 18 22 ] . The current biochemical results provide strong support for the hypothesis that MHCK-C acts as a MHC kinase in vivo.
MHCK-C differs from MHCK-A and MHCK-B in that it lacks any significant amino-terminal domain upstream of the catalytic domain; conserved catalytic domain residues are present within approximately 30 residues of the methionine start codon of MHCK-C (Figure 1).