Words similar to mhck-b
Example sentences for: mhck-b
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When the GFP fusions are imaged in myosin II null cells, both MHCK-A and MHCK-B display dynamics indistinguishable from their behaviour in cells wild type for myosin II.
Although MHCK-A has been extensively characterized at the biochemical level [ 18 22 25 31 ] , only limited biochemical analysis has been performed with bacterially-expressed subdomains of MHCK-B and MHCK-C [ 17 18 22 ] . The current biochemical results provide strong support for the hypothesis that MHCK-C acts as a MHC kinase in vivo.
Localization of MHCK-A and MHCK-B does not require myosin II.
However, the strong similarity of MHCK-C to MHCK-A and MHCK-B in the conserved catalytic domain and the carboxyl-terminal WD repeat domain suggested that it might represent a third myosin heavy chain kinase in this organism.
MHCK-C differs from MHCK-A and MHCK-B in that it lacks any significant amino-terminal domain upstream of the catalytic domain; conserved catalytic domain residues are present within approximately 30 residues of the methionine start codon of MHCK-C (Figure 1).
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