Words similar to mhck-c
Example sentences for: mhck-c
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Cloning of the cDNA encoding MHCK-C has been described [ 18 ] .
MHCK-C differs from MHCK-A and MHCK-B in that it lacks any significant amino-terminal domain upstream of the catalytic domain; conserved catalytic domain residues are present within approximately 30 residues of the methionine start codon of MHCK-C (Figure 1).
Another feature reported earlier for MHCK-A activation is that myosin II itself stimulates autophosphorylation [ 25 ] . To test whether MHCK-C autophosphorylation is accelerated in the presence of myosin II, the stoichiometry of FLAG-MHCK-C autophosphorylation was evaluated in the presence and absence of myosin II filaments.
Myosin II phosphorylation experiments revealed two additional features of MHCK-C biochemical behavior.
Our TIRF studies further support this model, suggesting that MHCK-C may physically associate with myosin II filaments.
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