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Example sentences for: mhcks

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Figure 11depicts our current working model for the dynamics of the three MHCKs during interphase (A), early cytokinesis (B) and late cytokinesis (C).
Distribution of GFP-labelled MHCKs (GFP-MHCK-A, -B and -C) was examined in live AX2 cells (containing an endogenous mhcA gene).
With the discovery of two additional myosin II heavy chain kinases, MHCK-B and MHCK-C, we report here in live migrating and cytokinetic cells a systematic in vivo examination of these three MHCKs labeled with GFP.
We suggest that differential localization of MHCKs occurs in D. discoideum cells for the purpose of regulating myosin II filament assembly levels in the context of specific cellular contractile events such as lamellipodium extension and cytokinetic furrowing.
In fact, the MHCKs are very likely to be highly regulated enzymes; previous studies have documented the in vitro regulation of MHCK A by autophosphorylation, myosin filaments, and acidic phospholipids [ 32 ] , and data presented here documents that MHCK C can also be regulated via autophosphorylation.