Words similar to mhcii-positive

Example sentences for: mhcii-positive

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Indeed, the CD4+ T cells that directly destroy MHCII-positive tumors were identified [ 5 ] . In the clinic, the expression of MHCII on colorectal carcinomas is correlated with more favourable prognosis [ 6 ] . Adoptive transfer studies show that ex vivo activated CD4+ T cells are able to recognize, and to eliminate, MHCII-positive tumors either by themselves [ 7 ] or in co-operation with CD8+ T cells [ 8 ] . It has been also demonstrated that the increased MHCII expression on tumor cells and macrophages following treatment with IFNg in vivo was associated with enhanced efficacy of adoptive T cell therapy in a mouse model of metastatic sarcoma [ 9 ] .