Words similar to mhcii

Example sentences for: mhcii

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It has been previously shown that potentiating effect of phorbol esters on IFNg-dependent MHCII induction in THP-1 monocytic cell line was associated with the increase in synthesis of IFNg receptors [ 19 ] . For that reason, we questioned whether PMA could produce similar changes in LS1034 colon carcinoma cells.
An experiment performed to assess contribution of each of the three sources demonstrated that: (1) non-specific binding of IgG2a-FITC was negligible in all experimental groups (Fig 8H); (2) tumor cells incubated with PMA alone did not bind anti-MHCII mAb above the level of isotype control and (3) tumor cells incubated with PMA (or with PMA+IFNg) demonstrated 1.2-1.
The LS1034 cells, on the other hand, demonstrated a robust increase in MHCII expression.
Further increases in concentration of IFNg (to 10 4IU/ml) did not result in statistically significant increases of MHCII expression (Figure 2B).
We also show that the IFNg-dependent MHCII expression in LS1034 cell line can be rescued by clinically acceptable concentrations of Bryostatin 1.