Words similar to mhc-peptide
Example sentences for: mhc-peptide
How can you use “mhc-peptide” in a sentence? Here are some example sentences to help you improve your vocabulary:
A number of computational methods have been developed for the prediction of MHC-peptide binding [ 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 ] . Using data from allele specific binding experiments - sequence binding motif analysis [ 10 ] ; weight matrices [ 11 12 13 ] , ANN [ 14 15 16 ] , HMM [ 17 ] and iterative stepwise discriminant meta-algorithm [ 18 ] have been applied for predictions.
The current challenge in MHC-peptide binding prediction is twofold: (1) accurate prediction of peptide backbone conformation for subsequent sidechain packing (2) accurate estimation of function by such predictions for quantitative MHC-peptide binding studies.
The critical nature of the backbone conformation that affects MHC-peptide binding will be interesting to investigate.
Protein threading [ 19 20 21 22 ] and side-chain packing [ 23 24 25 26 ] techniques have been applied in molecular mechanics based MHC-peptide binding predictions.
[ 23 ] have demonstrated a method for peptide backbone selection and showed a reasonable improvement in the MHC-peptide binding prediction.
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